Recombinant Mouse Mitogen-activated Protein Kinase 1, His-tagged
Cat.No. : | Mapk1-638M |
Product Overview : | Recombinant Mouse full length ERK2/MAPK2 (K52R) with N-terminal His6 tag, was expressed inE.coli. MW=42 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Mapk1-638M |
Description : | ERK2 is a protein serine/threonine kinase that is a member of the extracellular signal-regulated kinases (ERKs) which are activated in response to numerous growth factors and cytokines. Activation of ERK2 requires both tyrosine and threonine phosphorylation that is mediated by MEK. ERK2 is ubiquitously distributed in tissues with the highest expression in heart, brain and spinal cord. Activated ERK2 translocates into the nucleus where it phosphorylates various transcription factors. |
Source : | E.coli. |
Formulated In : | 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 50% glycerol, 3 mM DTT. |
Application : | A suitable substrate of MEK1. |
Stability : | >6 months at –80°C. |
Pathways : | Acute myeloid leukemia; Adherens junction; Aldosterone-regulated sodium reabsorption; Alzheimer"s disease; Axon guidance; Melanogenesis; Melanoma; NOD-like receptor signaling pathway; Natural killer cell mediated cytotoxicity; Neurotrophin signaling pathway; Non-small cell lung cancer; Oocyte meiosis; Pancreatic cancer; Pathways in cancer; Prion diseases; Progesterone-mediated oocyte maturation; Prostate cancer; Regulation of actin cytoskeleton; Renal cell carcinoma; T cell receptor signaling pathway; TGF-beta signaling pathway; Thyroid cancer; Toll-like receptor signaling pathway; Type II diabetes mellitus; VEGF signaling pathway; Vascular smooth muscle contraction; mTOR signaling pathway |
Gene Name : | Mapk1 mitogen-activated protein kinase 1 [ Mus musculus ] |
Synonyms : | mitogen-activated protein kinase 1; ERK; Erk2; MAPK2; PRKM2; Prkm1; C78273; p41mapk; p42mapk; AA407128; AU018647; 9030612K14Rik; Mapk1; ERT1; ERK-2; MAPK 1; MAPK 2; p42-MAPK; MAP kinase 1; MAP kinase 2; OTTMUSP00000021888; OTTMUSP00000022009; OTTMUSP00000022010; MAP kinase isoform p42; mitogen activated protein kinase 1; mitogen-activated protein kinase 2; extracellular signal-regulated kinase 2 |
Gene ID : | 26413 |
mRNA Refseq : | NM_001038663 |
Protein Refseq : | NP_001033752 |
UniProt ID : | P63085 |
Chromosome Location : | 16 A3; 16 9.82 cM |
Function : | mitogen-activated protein kinase kinase kinase binding; ATP binding; MAP kinase 2 activity; MAP kinase activity; kinase activity; nucleotide binding; phosphotyrosine binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; transcription factor binding; transferase activity |
Products Types
◆ Recombinant Protein | ||
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MAPK1-1081H | Recombinant Human MAPK1 Protein (M1-S360), Flag/His tagged | +Inquiry |
MAPK1-385H | Recombinant Human MAPK1 Protein, MYC/DDK-tagged | +Inquiry |
MAPK1-048H | Recombinant Human MAPK1 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
MAPK1-7267H | Recombinant Human MAPK1 protein(Met1-Ser360), GST-tagged | +Inquiry |
◆ Lysates | ||
MAPK1-001MCL | Recombinant Mouse MAPK1 cell lysate | +Inquiry |
MAPK1-692HCL | Recombinant Human MAPK1 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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