Active Recombinant Mouse Dll4 protein, His-tagged
Cat.No. : | Dll4-2288M |
Product Overview : | Recombinant Mouse Dll4 protein(NP_062327.2)(Met1-Pro525), fused with His tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Mouse |
Tag : | His |
Form : | Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA. |
Bio-activity : | 1. Immobilized DLL4 Protein, Mouse, Recombinant (His Tag) at 2 μg/mL (100 μL/well) can bind NOTCH1 Protein, Mouse, Recombinant (ECD, hFc Tag),the EC50 is 5-30 ng/mL.2. Measured by the ability of the immobilized protein to enhance BMP2-induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is typically 1-5 µg/mL in the presence of 500 ng/mL recombinant human BMP2. |
Molecular Mass : | The secreted recombinant mouse DLL4 comprises 509 amino acids and has a calculated molecular mass of 55.7 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 68 kDa band in SDS-PAGE under reducing conditions. |
Proteinlength : | Met1-Pro525 |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 96 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | Dll4 delta-like 4 (Drosophila) [ Mus musculus ] |
Official Symbol : | Dll4 |
Synonyms : | DLL4; delta-like 4 (Drosophila); delta-like protein 4; drosophila Delta homolog 4; Delta4; |
Gene ID : | 54485 |
mRNA Refseq : | NM_019454 |
Protein Refseq : | NP_062327 |
Products Types
◆ Recombinant Protein | ||
DLL4-202H | Recombinant Human DLL4 Protein, Fc-tagged | +Inquiry |
DLL4-2687H | Recombinant Human DLL4 Protein, GST-tagged | +Inquiry |
DLL4-1349H | Recombinant Human DLL4 Protein, His&GST-tagged | +Inquiry |
DLL4-001H | Recombinant Human DLL4 Protein, His-tagged | +Inquiry |
DLL4-1021R | Active Recombinant Rhesus DLL4 Protein (Met1-Pro528), His-tagged | +Inquiry |
◆ Lysates | ||
DLL4-2495MCL | Recombinant Mouse DLL4 cell lysate | +Inquiry |
DLL4-2507HCL | Recombinant Human DLL4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionDLL4 is implicated in the regulation of vascular inflammation and plaque formation, making it a potential target for atherosclerosis treatments.
DLL4 has been linked to Alzheimer's disease as it can influence amyloid-beta accumulation and the activation of microglia in the brain.
DLL4 levels can serve as a potential biomarker in some diseases, such as certain cancers, where it may indicate disease progression.
Challenges include potential side effects, the need for personalized treatment approaches, and the complexity of the Notch signaling pathway.
DLL4 can modulate tissue regeneration by influencing stem cell behavior and promoting tissue repair processes.
Customer Reviews (3)
Write a reviewThey ensure a consistent and reliable supply of DLL4 protein, minimizing any potential disruptions in my experimental workflow.
the manufacturer's commitment to scientific collaboration and knowledge sharing greatly enhances my research experience.
This collaborative approach empowers me to integrate cutting-edge knowledge, explore innovative techniques, and expand the impact of my research.
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