Goat Anti-Human CA1 Polyclonal Antibody

Cat.No.

CPBT-28970GH

Product Overview

Goat Polyclonal antibody to Human CA1.

Antigen Description

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Variants of this gene have been described in some populations. Multiple alternatively spliced variants, encoding the same protein, have been identified. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature.

Isotype

IgG

Immunogen

Carbonic Anhydrase I

Host

Goat

Species

Human

Formulation

Liquid

Purity Detail

Whole antiserum

Applications

WB, ELISA

Storage buffer

0.01M Na phosphate, 0.25M NaCl, pH7.6, 0.05% Na azide, 0.01% Thimerisol, 15mg/ml BSA

Storage

Store at +4^oC short term (1-2 weeks). Aliquot and store at -20^oC or -80^oC. Avoid repeated freeze / thaw cycles.

Sequence similarities

Belongs to the alpha-carbonic anhydrase family.

Antigen Gene Information