Recombinant Human Glutathione S-transferase Mu 1

• Cat.No.: GSTM1-2473H
• Product Overview: Recombinant Human GST M1 was expressed inE. coli.MW= 26 kDa.

Specification

• Cat. No.: GSTM1-2473H
• Description: Glutathione S-transferase Mu 1 (gene name GSTM1) is a human glutathione S-transferase. Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a cytoplasmic glutathione S-transferase that belongs to the mu class.
• Source: E. coli.
• Specific Activity: 68.9 Units/mg using spectrophotometric determination of 1-chloro-2,4-dinitrobenzene (CDNB) conjugation with reduced glutathione (1 mM) in 100 mM NaPO4 (pH 6.5) at room temperature.
• Concentration: 2.4 mg/mL total protein using the Bradford protein assay with BSA as a standard.
• Storage Buffer: 50 mM Tris-HCl (pH 7.5), 50 mM NaCl, 1 mM DTT, 5 mM EDTA and 50% glycerol.
• Purity: ≥95% as assessed by inspection on a Coomassie® Blue-stained SDS-PAGE gel.
• Storage: -20˚C; avoid multiple freeze-thaw cycles.

Gene Information

• Gene Name: GSTM1 glutathione S-transferase mu 1 [ Homo sapiens ]
• Synonyms: glutathione S-transferase mu 1; MU; H-B; GST1; GTH4; GTM1; MU-1; GSTM1-1; MGC26563; GSTM1a-1a; GSTM1b-1b; GSTM1; glutathione S-transferase Mu 1; HB subunit 4; GST class-mu 1; GST HB subunit 4; glutathione S-transferase M1; glutathione S-aryltransferase; glutathione S-alkyltransferase; glutathione S-aralkyltransferase; S-(hydroxyalkyl)glutathione lyase;EC 2.5.1.18
• Gene ID: 2944
• mRNA Refseq: NM_000561
• Protein Refseq: NP_000552
• MIM: 138350
• UniProt ID: P09488
• Chromosome Location: 1p13.3
• Pathway: Drug metabolism - cytochrome P450; Glutathione metabolism; Metabolism of xenobiotics by cytochrome P450; Biological oxidations
• Function: glutathione transferase activity; transferase activity