Recombinant Mouse Serpine1
| Cat.No. : | Serpine1-2462M |
| Product Overview : | Recombinant Mouse Serpine1 was expressed inE.Coli.It was the ideal choice for studies involving this animal model of fibrinolysis and cancer studies. The active fraction typically contained 70 percent active PAI-1. MW=43 KDa. |
- Specification
- Gene Information
- Related Products
| Cat. No. : | Serpine1-2462M |
| Description : | Plasminogen activator inhibitor-1 is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), the activators of plasminogen and hence fibrinolysis (the physiological breakdown of blood clots). It is a serine protease inhibitor (serpin) protein (SERPINE1).The other PAI, plasminogen activator inhibitor-2 (PAI-2) is secreted by the placenta and only present in significant amounts during pregnancy. In addition, protease nexin acts as an inhibitor of tPA and urokinase. PAI-1, however, is the main inhibitor of the plasminogen activators. |
| Source : | E.Coli. |
| Concentration : | 2.5 mg/ml. |
| Volume : | 0.2 ml. |
| Buffer : | 0.05 M Sodium Acetate; 0.1 M NaCl; 1 mM EDTA; pH 5.0. |
| Form : | Frozen liquid. |
| Shipping Information : | Recommended Storage: -70℃; Shipping Conditions: Dry ice; Minimum Shelf Life: 3 years from delivery. |
| Gene Name : | Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 [ Mus musculus ] |
| Synonyms : | Serpine1; serine (or cysteine) peptidase inhibitor, clade E, member 1; PAI1; PAI-1; Planh1; plasminogen activator inhibitor 1; PAI; serpin E1; plasminogen activator inhibitor, type I; endothelial plasminogen activator inhibitor; nexin, plasminogen activator inhibitor type 1; serine (or cysteine) proteinase inhibitor, clade E, member 1; Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI) |
| Gene ID : | 18787 |
| mRNA Refseq : | NM_008871 |
| Protein Refseq : | NP_032897 |
| UniProt ID : | P22777 |
| Chromosome Location : | 5 G2 |
| Pathway : | Chagas disease; Complement and coagulation cascades; p53 signaling pathway |
| Function : | peptidase inhibitor activity; protein binding; serine-type endopeptidase activity; serine-type endopeptidase inhibitor activity |
Products Types
| ◆ Native Protein | ||
| SERPINE1-5514R | Native Rabbit Serpin Peptidase Inhibitor, Clade E (nexin, plasminogen activator inhibitor type 1), Member 1 | +Inquiry |
| SERPINE1-29522TH | Native Human SERPINE1 | +Inquiry |
| ◆ Lysates | ||
| SERPINE1-001RCL | Recombinant Rat SERPINE1 cell lysate | +Inquiry |
| SERPINE1-2383HCL | Recombinant Human SERPINE1 cell lysate | +Inquiry |
| ◆ Assay kits | ||
| Kit-0782 | SERPINE1 (Human) Chromogenic Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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