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Cat.No.
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CPBT-29745RH
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Product Overview
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Rabbit Polyclonal antibody to Human CHRND.
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Antigen Description
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The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits.After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
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Isotype
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IgG
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Immunogen
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A region within synthetic peptide: KKGYNKELRP VAHKEESVDV ALALTLSNLI SLKEVEETLT TNVWIEHGWT, corresponding to N terminal amino acids 36-85 of Human CHRND
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Host
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Rabbit
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Species
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Human
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Formulation
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Liquid
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Purity Detail
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Immunogen affinity purified
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Applications
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ELISA, WB
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Storage buffer
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Preservative: None Constituents: 2% Sucrose, PBS
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Storage
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Shipped at 4oC. Upon delivery aliquot and store at -20oC. Avoid freeze / thaw cycles.
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Sequence similarities
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Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Delta/CHRND sub-subfamily.
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Antigen Gene Information
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Gene Name
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CHRND cholinergic receptor, nicotinic, delta [ Homo sapiens ]
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Official Symbol
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CHRND
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Synonyms
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CHRND; cholinergic receptor, nicotinic, delta; ACHRD, cholinergic receptor, nicotinic, delta polypeptide; acetylcholine receptor subunit delta; Acetylcholine receptor delta subunit; Acetylcholine receptor subunit delta; ACHD_HUMAN; ACHRD; Cholinergic receptor, nicotinic, delta polypeptide; CHRND; CMS2A; FCCMS; HGNC:1965; Nicotinic acetylcholine receptor delta polypeptide precursor; SCCMS; cholinergic receptor, nicotinic, delta polypeptide; ACHRD; CMS2A; FCCMS; SCCMS;
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GeneID
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1144
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mRNA Refseq
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NM_000751
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Protein Refseq
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NP_000742
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MIM
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100720
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Uniprot ID
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Q07001
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Chromosome Location
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2q33-qter
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Pathway
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Acetylcholine Binding And Downstream Events, organism-specific biosystem; Activation of Nicotinic Acetylcholine Receptors, organism-specific biosystem; Highly sodium permeable acetylcholine nicotinic receptors, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
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Function
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acetylcholine-activated cation-selective channel activity; extracellular ligand-gated ion channel activity; ion channel activity; receptor activity;
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Download Datasheet:
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