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Cat.No.
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CPBT-31417GH
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Product Overview
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Goat Polyclonal antibody to Human DLGAP1.
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Antigen Description
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Disks large-associated protein 1 (DAP-1), also known as guanylate kinase-associated protein (GKAP) is a protein that in humans is encoded by the DLGAP1 gene. DAP-1 is known to be highly enriched in synaptosomal preparations of the brain, and present in the post synaptic densityThis gene encodes the protein called guanylate kinase-associated protein (GKAP). GKAP binds to the SHANK and PSD-95 proteins fascilitating the assembly of the post synaptic density of neurons.Dlgap1 has five 14-amino acid repeats and three Pro-rich portions.
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Isotype
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IgG
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Immunogen
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A synthetic peptide from the internal region of Human DLGAP1.
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Host
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Goat
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Species
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Human
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Specificity
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Expressed in brain.
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Formulation
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Liquid
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Purity Detail
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Immunogen affinity purified
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Applications
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IHC-P
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Storage buffer
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pH: 7.30Preservative:0.02% Sodium azide Constituents:Tris buffered saline, 0.5% BSA
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Storage
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Store at +4oC short term (1-2 weeks). Aliquot and store at -20oC long term. Avoid repeated freeze / thaw cycles.
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Sequence similarities
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Belongs to the SAPAP family.
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Antigen Gene Information
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Gene Name
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DLGAP1 discs, large (Drosophila) homolog-associated protein 1 [ Homo sapiens ]
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Official Symbol
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DLGAP1
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Synonyms
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DLGAP1; discs, large (Drosophila) homolog-associated protein 1; discs, large (Drosophila) homolog associated protein 1; disks large-associated protein 1; DAP 1; GKAP; SAPAP1; 9630002F18; AI845682; AI848168; BB075781; D17Bwg0511e; DAP 1 ALPHA; DAP 1; DAP 1 BETA; GKPA/SAPAP; hGKAP; KIAA4162; mKIAA4162; SAPAP1; 4933422O14Rik; DAP1; Discs large (Drosophila) homolog associated protein 1; Discs large homolog associated protein 1; Disks large associated protein 1; Disks large associated protein 1, alpha isoform, included; Disks large associated protein 1, beta isoform, included; DLGAP 1; Dlgap1; GKAP; GKAP/SAPAP; Guanylate kinase associated protein; MGC88156; PSD 95/SAP90 binding protein 1; SAP90/PSD 95 associated protein 1; SAPAP 1; PSD-95/SAP90 binding protein 1; SAP90/PSD-95-associated protein 1; guanylate kinase-associated protein; DAP-1; hGKAP; DAP-1-BETA; DAP-1-ALPHA;
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GeneID
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9229
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mRNA Refseq
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NM_001242765
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Protein Refseq
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NP_001229694
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MIM
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605445
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Uniprot ID
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O14490
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Chromosome Location
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18p11.3
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Pathway
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Glutamatergic synapse, organism-specific biosystem; Glutamatergic synapse, conserved biosystem;
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Function
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protein binding; protein domain specific binding;
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Download Datasheet:
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