Recombinant Human ACE2, His-tagged
Cat.No. : | ACE2-745H |
Product Overview : | Recombinant human ACE-2 ectodomain (amino acids 1-740) was fused at the C-terminus to a His•Tag sequence and expressed inNSO cells. By SDS-PAGE, the apparent molecular mass of the glycosylated protein is ~120 kDa under either reducing or non-reducing conditions. |
- Specification
- Gene Information
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Cat. No. : | ACE2-745H |
Description : | ACE-2 cleaves angiotensins I and II as a carboxypeptidase and plays an important role in regulating cardiovascular and renal functions. Native ACE-2 is an integral membrane zinc metalloprotease whose activity is inhibited by EDTA. |
Source : | Mammalian cells |
Purity : | ≥90% by SDS-PAGE. |
Form : | Liquid. Please refer to vial label for lot-specific concentration. |
Endotoxins : | ≤1.0 EU/µg ACE-2. |
Specific Activity : | ≥0.8 unit/µg protein. |
Unit Definition : | One unit is defined as the amount of enzyme that will cleave 1 nmol MCA-YVADAPK(DNP)-OH per min at 25℃, pH 7.5. |
Toxicity : | Standard Handling (MSDS available upon request). |
Storage : | ≤ -70℃. Avoid freeze/thaw. Following initial thaw, aliquot and freeze (-70℃). |
Gene Name : | ACE2 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 [ Homo sapiens ] |
Synonyms : | ACE2; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; ACEH; DKFZp434A014; angiotensin I converting enzyme; ACE-related carboxypeptidase2; angiotensin converting enzyme-like protein; EC 3.4.15.1; EC 3.4.17.-; Angiotensin-converting enzyme 2; ACEH |
Gene ID : | 59272 |
mRNA Refseq : | NM_021804 |
Protein Refseq : | NP_068576 |
MIM : | 300335 |
UniProt ID : | Q9BYF1 |
Chromosome Location : | Xp22 |
Pathway : | Renin-angiotensin system |
Function : | carboxypeptidase activity; chloride ion binding; glycoprotein binding; metal ion binding; metallopeptidase activity; peptidase activity; peptidyl-dipeptidase activity; viral receptor activity; zinc ion binding |
Products Types
◆ Lysates | ||
ACE2-1851RCL | Recombinant Rat ACE2 cell lysate | +Inquiry |
ACE2-887CCL | Recombinant Cynomolgus ACE2 cell lysate | +Inquiry |
ACE2-2085MCL | Recombinant Mouse ACE2 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-2210 | Angiotensin II Converting Enzyme (ACE2) Activity Assay Kit (Fluorometric) | +Inquiry |
Kit-2101 | Angiotensin II Converting Enzyme Inhibitor Screening Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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