Recombinant Human MAPKAPK5, GST-His
Cat.No. : | MAPKAPK3-695H |
Product Overview : | Recombinant, human MAPKAPK5 is fused at the N-terminus to a GST-His 6-thrombin cleavage site tag and expressed inS. frugiperda insect cellsusing a baculovirus expression system. MAPKAPK5 is a member of the serine/threonine kinase family that mediates stress-induced small heat shock protein 27 phosphorylation. |
- Specification
- Gene Information
- Related Products
Cat. No. : | MAPKAPK3-695H |
Description : | MAP kinase-activated protein kinase 5 is an enzyme that in humans is encoded by the MAPKAPK5 gene. The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. |
Source : | S. frugiperda insect cells. |
Form : | Liquid. |
Formulation : | In 100 mM NaCl, 50 mM Tris-HCl, 5 mM DTT, 4 mM reduced glutathione, 20% glycerol, pH 8.0. |
Molar Mass : | 84116 Da. |
Specific Activity : | ≥2 U/mg protein. |
Unit Definition : | One unit is defined as the amount of enzyme required to transfer 1 nmol phosphate to tetra(LRRWSLG) per min at 30°C using concentration of 0.1 μM ATP. |
Purity : | ≥90% by SDS-PAGE. |
Storage : | ≤ -70oC. Ship: Dry Ice Only. |
Gene Name : | MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 [ Homo sapiens ] |
Synonyms : | MAPKAPK5; mitogen-activated protein kinase-activated protein kinase 5; MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; MAPKAPK-5; p38-regulated/activated protein kinase; PRAK; EC 2.7.11.1 |
Gene ID : | 8550 |
mRNA Refseq : | NM_003668 |
Protein Refseq : | NP_003659 |
MIM : | 606723 |
UniProt ID : | Q8IW41 |
Chromosome Location : | 12q24.12-q24.13 |
Pathway : | MAPK signaling pathway |
Function : | ATP binding; MAP kinase kinase activity; nucleotide binding; protein |
Products Types
◆ Recombinant Protein | ||
MAPKAPK5-5358M | Recombinant Mouse MAPKAPK5 Protein, His (Fc)-Avi-tagged | +Inquiry |
MAPKAPK5-1303H | Recombinant Human MAPKAPK5 Protein (S2-Q473), Tag Free | +Inquiry |
MAPKAPK5-2495R | Recombinant Rhesus Macaque MAPKAPK5 Protein, His (Fc)-Avi-tagged | +Inquiry |
MAPKAPK5-1304H | Recombinant Human MAPKAPK5 Protein (S2-Q473), GST tagged | +Inquiry |
MAPKAPK5-1216H | Recombinant Human MAPKAPK5 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
MAPKAPK5-432HCL | Recombinant Human MAPKAPK5 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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