Recombinant Human Rap Guanine Nucleotide Exchange Factor (GEF) 4
Cat.No. : |
RAPGEF4-2637H |
Product Overview : |
Recombinant human Rap Guanine Nucleotide Exchange Factor (GEF) 4 is expressed inE. coli. |
- Specification
- Gene Information
- Related Products
Cat. No. : |
RAPGEF4-2637H |
Description : |
Rap guanine nucleotide exchange factor (GEF) 4 (RAPGEF4), also known as exchange protein directly activated by cAMP 2 (EPAC2), is a protein which in humans is encoded by the RAPGEF4 gene. |
Source : |
E.coli. |
Form : |
Liquid. |
Formulation : |
In 150 mM NaCl, 10 mM Tris, 0.1% NP-40, pH 8.3. |
Biological Activity : |
EC50 of cAMP binding: ≤1.5 μM. |
Storage : |
+2°C to +8°C. Ship: Dry Ice Only. |
Gene Name : |
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 [ Homo sapiens ] |
Synonyms : |
RAPGEF4; Rap guanine nucleotide exchange factor (GEF) 4; EPAC 2; OTTHUMP00000205058; RAP guanine-nucleotide-exchange factor (GEF) 4; cAMP-regulated guanine nucleotide exchange factor II; exchange factor directly activated by cAMP 2; exchange protein directly activated by cAMP 2; putative protein product of Nbla00496; rap guanine nucleotide exchange factor 4; CGEF2; EPAC2; Nbla00496; CAMP-GEFII |
Gene ID : |
11069 |
mRNA Refseq : |
NM_001100397 |
Protein Refseq : |
NP_001093867 |
MIM : |
606058 |
UniProt ID : |
Q8WZA2 |
Chromosome Location : |
2q31-q32 |
Pathway : |
Leukocyte transendothelial migration; Diabetes pathways; Integration of energy metabolism; Integrin cell surface interactions |
Function : |
Ras GTPase binding; Ras guanyl-nucleotide exchange factor activity; cAMP binding; cAMP-dependent protein kinase regulator activity; guanyl-nucleotide exchange factor activity; nucleotide binding; protein binding |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.