Recombinant Human Selectin E

• Cat.No.: SELE-2638H
• Product Overview: Recombinant human Selectin E consisting of 535 amino acids is expressed inCHO cells.

Specification

• Cat. No.: SELE-2638H
• Description: E-selectin, also known as CD62E, is a cell adhesion molecule expressed only on endothelial cells activated by cytokines. Like other selectins, it plays an important part in inflammation. In humans, E-selectin is encoded by the SELE gene. E-selectin recognizes and binds to sialylated carbohydrates present on the surface proteins of certain leukocytes. These carbohydrates include members of the Lewis X and Lewis A families found on monocytes, granulocytes, and T-lymphocytes.
• Source: CHO cells.
• Form: Lyophilized.
• Formulation: Lyophilized from Dulbecco"s PBS with stabilizer.
• Molar Mass: 58800 Da.
• Biological Activity: Shown to bind to E-selectin ligands on U937 cells.
• Purity: ≥95% by SDS-PAGE.
• Storage: ≤ -20oC. Ship: Dry Ice Only.
• Publication:
  A computational and experimental study to develop E-selectin targeted peptides for molecular imaging applications (2018)

Gene Information

• Gene Name: SELE selectin E [ Homo sapiens ]
• Synonyms:
  SELE; selectin E; CD62 antigen-like family member E; E-selectin; ELAM-1; OTTHUMP00000032746; OTTHUMP00000032747; OTTHUMP00000032748; OTTHUMP00000032749; endothelial adhesion molecule 1; endothelial leukocyte adhesion molecule 1; leukocyte endothelial cell adhesion molecule 2; leukocyte-endothelial cell adhesion molecule 2; ELAM; ESEL; CD62E; ELAM1; LECAM2
• Gene ID: 6401
• mRNA Refseq: NM_000450
• Protein Refseq: NP_000441
• MIM: 131210
• UniProt ID: P16581
• Chromosome Location: 1q22-q25
• Pathway: Cell adhesion molecules (CAMs); Malaria
• Function: binding; oligosaccharide binding; phospholipase binding; sialic acid binding; sugar binding; transmembrane receptor activity