Active Recombinant Bovine Interleukin 6 (Interferon, Beta 2)
Cat.No. : | IL6-241B |
Product Overview : | Recombinant Bovine IL-6 was expressed inYeast. MW= 20.7 kDa (179 aa). |
- Specification
- Gene Information
- Related Products
Cat. No. : | IL6-241B |
Description : | Interleukin-6 (IL-6) is a protein that in humans is encoded by the IL6 gene. IL-6 is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. In terms of host response to a foreign pathogen, IL-6 has been shown, in mice, to be required for resistance against the bacterium, Streptococcus pneumoniae. IL-6 is also a "myokine," a cytokine produced from muscle, and is elevated in response to muscle contraction. |
Source : | Yeast. |
Formulation/ Reconstitution : | Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. |
Purification : | Ion-exchange chromatography. |
Purity : | >95% as visualized by SDS-PAGE analysis. |
Amino Acid Sequence : | GPLGEDFKND TTPGRLLLTT PEKTEALIKR MVDKISAMRK EICEKNDECE SSKETLAENK LNLPKMEEKD GCFQSGFNQA ICLIRTTAGL LEYQIYLDYL QNEYEGNQEN VRDLRKNIRT LIQILKQKIA DLITTPATNT DLLEKMQSSN EWVKNAKIIL ILRNLENFLQ FSLRAIRMK. |
Bioactivity : | Currently, there is no known bioassay for bovine IL-6. |
Stability And Storage : | Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles. |
Gene Name : | IL6 interleukin 6 (interferon, beta 2) [ Bos taurus ] |
Synonyms : | interleukin 6 (interferon, beta 2); IL6; interleukin-6; IL-6 |
Gene ID : | 280826 |
mRNA Refseq : | NM_173923.2 |
Protein Refseq : | NP_776348.1 |
UniProt ID : | P26892 |
Chromosome Location : | 4 |
Pathway : | Cytokine-cytokine receptor interaction; Cytosolic DNA-sensing pathway; Graft-versus-host disease; Hematopoietic cell lineage; Hypertrophic cardiomyopathy (HCM); Intestinal immune network for IgA production; Jak-STAT signaling pathway; NOD-like receptor signaling pathway; Pathways in cancerPrion diseases; Toll-like receptor signaling pathway |
Function : | cytokine activity; growth factor activity; interleukin-6 receptor binding; protein binding |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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