Recombinant Human Uridine-cytidine Kinase 2, His-tagged
Cat.No. : | UCK2-930H |
Product Overview : | Recombinant human UCK2 protein, fused to His-tag at C-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 30.3kDa (269aa). |
- Specification
- Gene Information
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Cat. No. : | UCK2-930H |
Description : | UCK2 also known as uridine-cytidine kinase 2 is belongs to the uridinekinase family. UCK2 catalyzes the phosphorylation of uridine monophosphate to uridine diphosphate and cytidine monophosphate. It plays a role in the production of pyrimidine nucleoside triphosphates required for RNA and DNA synthesis. In addition, an allele of this gene may play a role in mediating nonhumoral immunity to Hemophilus influenzae type B. |
Source : | E.coli. |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 2mM DTT, 100mM NaCl, 0.1mM PMSF, 1mM EDTA. |
Purity : | > 90% by SDS - PAGE. |
Concentration : | 1mg/ml (determined by Bradford assay). |
Sequences Of Amino Acids : | MAGDSEQTLQ NHQQPNGGEP FLIGVSGGTA SGKSSVCAKI VQLLGQNEVD YRQ KQVVILS QDSFYRVLTS EQKAKALKGQ FNFDHPDAFD NELILKTLKE ITEGKTVQIP VYDFVSHSRK EETVTVYPAD VVLFEGILAF YSQEVRDLFQ MKLFVDTDAD TRL SRRVLRD ISERGRDLEQ ILSQYITFVK PAFEEFCLPT KKYADVIIPR GADNLVAINL IVQHIQDILN GGPSKRQTNG CLNGYTPSRK RQASESSSRP HLEHHHHHH. |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Pathways : | Drug metabolism - other enzymes; Metabolic pathways; Pyrimidine metabolism; Metabolism of nucleotides |
Gene Name : | UCK2 uridine-cytidine kinase 2 [ Homo sapiens ] |
Synonyms : | uridine-cytidine kinase 2; UK; UMPK; TSA903; UCK2; uridine kinase; uridine monophosphokinase 2; cytidine monophosphokinase 2; uridine monophosphate kinase; testis-specific protein TSA903; Uridine monophosphokinase 2; Cytidine monophosphokinase 2; Testis-specific protein TSA903; EC 2.7.1.48 |
Gene ID : | 7371 |
mRNA Refseq : | NM_012474 |
Protein Refseq : | NP_036606 |
MIM : | 609329 |
UniProt ID : | Q9BZX2 |
Chromosome Location : | 1q23 |
Function : | ATP binding; kinase activity; molecular_function; nucleotide binding; phosphotransferase activity, alcohol group as acceptor; transferase activity; uridine kinase activity |
Products Types
◆ Recombinant Protein | ||
UCK2-2306H | Recombinant Human UCK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Uck2-6823M | Recombinant Mouse Uck2 Protein, Myc/DDK-tagged | +Inquiry |
UCK2-4901R | Recombinant Rhesus Macaque UCK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
UCK2-30101TH | Recombinant Human UCK2, His-tagged | +Inquiry |
UCK2-3953C | Recombinant Chicken UCK2 | +Inquiry |
◆ Lysates | ||
UCK2-531HCL | Recombinant Human UCK2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, UCK2 protein levels can be quantified in patient samples using techniques such as immunohistochemistry and ELISA for clinical assessment.
Certain genetic mutations in the UCK2 gene have been linked to altered UCK2 protein function, which may impact clinical outcomes in certain diseases.
Some studies have suggested a potential link between UCK2 protein and neurological disorders, although further research is needed to fully understand this association.
UCK2 protein has been implicated in liver diseases, particularly in the context of nucleoside analog metabolism and liver cell function.
UCK2 protein has been associated with drug resistance in cancer cells, particularly in the context of chemotherapy.
Customer Reviews (3)
Write a reviewI highly endorse the utilization of the UCK2 Protein for researchers seeking a superior protein solution that not only meets their experimental needs but also benefits from the exceptional technical support provided by the manufacturer.
Their expertise has proven instrumental in overcoming obstacles and has greatly contributed to the success of my research endeavors.
Their team of experts has been extremely helpful in addressing any concerns or queries I encountered during my experiments.
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