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Recombinant Human Uridine-cytidine Kinase 2, His-tagged

Cat.No. : UCK2-930H
Product Overview : Recombinant human UCK2 protein, fused to His-tag at C-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 30.3kDa (269aa).
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Cat. No. : UCK2-930H
Description : UCK2 also known as uridine-cytidine kinase 2 is belongs to the uridinekinase family. UCK2 catalyzes the phosphorylation of uridine monophosphate to uridine diphosphate and cytidine monophosphate. It plays a role in the production of pyrimidine nucleoside triphosphates required for RNA and DNA synthesis. In addition, an allele of this gene may play a role in mediating nonhumoral immunity to Hemophilus influenzae type B.
Source : E.coli.
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 2mM DTT, 100mM NaCl, 0.1mM PMSF, 1mM EDTA.
Purity : > 90% by SDS - PAGE.
Concentration : 1mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MAGDSEQTLQ NHQQPNGGEP FLIGVSGGTA SGKSSVCAKI VQLLGQNEVD YRQ KQVVILS QDSFYRVLTS EQKAKALKGQ FNFDHPDAFD NELILKTLKE ITEGKTVQIP VYDFVSHSRK EETVTVYPAD VVLFEGILAF YSQEVRDLFQ MKLFVDTDAD TRL SRRVLRD ISERGRDLEQ ILSQYITFVK PAFEEFCLPT KKYADVIIPR GADNLVAINL IVQHIQDILN GGPSKRQTNG CLNGYTPSRK RQASESSSRP HLEHHHHHH.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways : Drug metabolism - other enzymes; Metabolic pathways; Pyrimidine metabolism; Metabolism of nucleotides
Gene Name : UCK2 uridine-cytidine kinase 2 [ Homo sapiens ]
Synonyms : uridine-cytidine kinase 2; UK; UMPK; TSA903; UCK2; uridine kinase; uridine monophosphokinase 2; cytidine monophosphokinase 2; uridine monophosphate kinase; testis-specific protein TSA903; Uridine monophosphokinase 2; Cytidine monophosphokinase 2; Testis-specific protein TSA903; EC 2.7.1.48
Gene ID : 7371
mRNA Refseq : NM_012474
Protein Refseq : NP_036606
MIM : 609329
UniProt ID : Q9BZX2
Chromosome Location : 1q23
Function : ATP binding; kinase activity; molecular_function; nucleotide binding; phosphotransferase activity, alcohol group as acceptor; transferase activity; uridine kinase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can UCK2 protein levels in patient samples be measured for clinical assessment? 12/04/2021

Yes, UCK2 protein levels can be quantified in patient samples using techniques such as immunohistochemistry and ELISA for clinical assessment.

Are there any genetic mutations associated with UCK2 protein that impact clinical outcomes? 05/15/2020

Certain genetic mutations in the UCK2 gene have been linked to altered UCK2 protein function, which may impact clinical outcomes in certain diseases.

Does UCK2 protein have any role in neurological disorders? 03/01/2019

Some studies have suggested a potential link between UCK2 protein and neurological disorders, although further research is needed to fully understand this association.

How is UCK2 protein involved in liver diseases? 03/31/2018

UCK2 protein has been implicated in liver diseases, particularly in the context of nucleoside analog metabolism and liver cell function.

What role does UCK2 protein play in drug resistance in cancer? 03/19/2016

UCK2 protein has been associated with drug resistance in cancer cells, particularly in the context of chemotherapy.

Customer Reviews (3)

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Reviews
08/24/2022

    I highly endorse the utilization of the UCK2 Protein for researchers seeking a superior protein solution that not only meets their experimental needs but also benefits from the exceptional technical support provided by the manufacturer.

    10/09/2021

      Their expertise has proven instrumental in overcoming obstacles and has greatly contributed to the success of my research endeavors.

      05/07/2020

        Their team of experts has been extremely helpful in addressing any concerns or queries I encountered during my experiments.

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