Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human Hydroxyacylglutathione Hydrolase, His-tagged

Cat.No. : HAGH-932H
Product Overview : Recombinant human HAGH protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography. MW = 31.4 kDa (284aa).
  • Specification
  • Gene Information
  • Related Products
Cat. No. : HAGH-932H
Description : HAGH is a member of the glyoxalase family and a thiolesterase which hydrolyses S-lactoyl-glutathione to reduced glutathione and D-lactate. This protein is a detoxifying enzyme of glycolysis byproduct methylglyoxal and a target of p63 and p73 and serves as a pro-survival factor of the p53 family. It exists only as a monomer and binds two zinc ions per subunit.
Source : E.coli.
Form : Liquid. In 20 mM Tris-HCl Buffer (pH 8.5) containing 10% Glycerol.
Purity : > 95% by SDS - PAGE.
Concentration : 0.5 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MGSHMKVEVL PALTDNYMYL VIDDETKEAA IVDP VQPQKV VDAARKHGVK LTTVLTTHHH WDHAGGNEKLVKLESGLKVY GGDD RIG ALT HKITHLSTLQ VGSLNVKCLA TPCHTSGHIC YFVSKPGGSE PPAVFTGDTL FVAG CGKFYE GTADEMCKALLEVLGRLPPD TRVYCGHEYT INNLKFARHV EPGN AAIREK LAWAKEKYSI GEPTVPSTLA EEFTYNPFMR VREKTVQQHA GETDP VTTMR AVRREKDQFK MPRD.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways : Pyruvate metabolism
Gene Name : HAGH hydroxyacylglutathione hydrolase [ Homo sapiens ]
Synonyms : hydroxyacylglutathione hydrolase; GLO2; GLX2; GLXII; HAGH1; HAGH; hydroxyacylglutathione hydrolase, mitochondrial; glx II; glyoxalase II; hydroxyacylglutathione hydroxylase; hydroxyacyl glutathione hydrolase; EC 3.1.2.6; Glyoxalase II; Glx II
Gene ID : 3029
mRNA Refseq : NM_001040427
Protein Refseq : NP_001035517
MIM : 138760
UniProt ID : Q16775
Chromosome Location : 16p13.3
Function : hydrolase activity; hydroxyacylglutathione hydrolase activity; metal ion binding; zinc ion binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All HAGH Products

Required fields are marked with *

My Review for All HAGH Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends