Recombinant Canine Interleukin 6 (Interferon, Beta 2)
| Cat.No. : | IL6-244C |
| Product Overview : | Recombinant Canine IL-6 was expressed inYeast. MW= 21.0 kDa (187 aa). |
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- Gene Information
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| Cat. No. : | IL6-244C |
| Description : | Interleukin-6 (IL-6) is a protein that in humans is encoded by the IL6 gene. IL-6 is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. In terms of host response to a foreign pathogen, IL-6 has been shown, in mice, to be required for resistance against the bacterium, Streptococcus pneumoniae. IL-6 is also a "myokine," a cytokine produced from muscle, and is elevated in response to muscle contraction. |
| Source : | Yeast. |
| Formulation/ Reconstitution : | Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. |
| Purification : | Ion-exchange chromatography. |
| Purity : | >95% as visualized by SDS-PAGE analysis. |
| Amino Acid Sequence : | FPTPGPLAGD SKDDATSNSL PLTSANKVEE LIKYILGKIS ALRKEMCDKF NKCEDSKEAL AENNLHLPKL EGKDGCFQSG FNQETCLTRI TTGLVEFQLH LNILQNNYEG DKENVKSVHM STKILVQMLK SKVKNQDEVT TPDPTTDASL QAILQSQDEW LKHTTIHLIL RSLEDFLQFS LRAVRIM. |
| Bioactivity : | In testing. |
| Stability And Storage : | Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles. |
| Gene Name : | IL6 interleukin 6 (interferon, beta 2) [ Canis lupus familiaris ] |
| Synonyms : | interleukin 6 (interferon, beta 2); IL6; IL-6; interleukin-6 |
| Gene ID : | 403985 |
| mRNA Refseq : | NM_001003301.1 |
| Protein Refseq : | NP_001003301.1 |
| UniProt ID : | P41323 |
| Chromosome Location : | 14 |
| Pathway : | Cytokine-cytokine receptor interaction; Cytosolic DNA-sensing pathway; Graft-versus-host disease; Hematopoietic cell lineage; Hypertrophic cardiomyopathy (HCM); Intestinal immune network for IgA production; Jak-STAT signaling pathway; NOD-like receptor signaling pathway; Pathways in cancer; Prion diseases; Toll-like receptor signaling pathway |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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