Catalog # or name ...
Rabbit Polyclonal antibody to Human ARHGAP26.
Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Two transcript variants encoding different isoforms have been found for this gene.
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the sequence of human GRAF within aa 200-300
Protein G purified
IHC-P, ELISA, WB
Preservative: 0.09% Sodium AzideConstituents: PBS
Store at +4oC short term (1-2 weeks). Aliquot and store at -20oC or -80oC. Avoid repeated freeze / thaw cycles.
Antigen Gene Information
ARHGAP26 Rho GTPase activating protein 26 [ Homo sapiens ]
ARHGAP26; Rho GTPase activating protein 26; rho GTPase-activating protein 26; GRAF; GTPase regulator associated with the focal adhesion kinase pp125; KIAA0621; OPHN1L; OPHN1L1; ARHGAP26; GTPase regulator associated with focal adhesion kinase pp125(FAK); OPHN1L; Rho GTPase activating protein 26; oligophrenin-1-like protein; GTPase regulator associated with focal adhesion kinase pp125(FAK); GRAF1;
Rho GTPase cycle, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by Rho GTPases, organism-specific biosystem; Signaling events mediated by focal adhesion kinase, organism-specific biosystem;
GTPase activator activity; Rho GTPase activator activity; SH3 domain binding; cytoskeletal adaptor activity; protein binding;
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