Catalog # or name ...
Rabbit Polyclonal antibody to Human IRAK1.
This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synthetic phosphopeptide derived from human IRAK around the phosphorylation site of threonine 209 (R-G-TP-H-N).
Isoform 1 and isoform 2 are ubiquitously expressed in all tissues examined, with isoform 1 being more strongly expressed than isoform 2.
Immunogen affinity purified
ELISA, WB, ICC/IF
Preservative: 0.02% Sodium AzideConstituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4
Shipped at 4oC. Upon delivery aliquot and store at -20oC. Avoid freeze / thaw cycles.
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.Contains 1 protein kinase domain.
Antigen Gene Information
IRAK1 interleukin-1 receptor-associated kinase 1 [ Homo sapiens ]
IRAK1; interleukin-1 receptor-associated kinase 1; IRAK; pelle; Il1rak; Interleukin 1 receptor associated kinase 1; Interleukin 1 receptor associated kinase 2; Interleukin-1 receptor-associated kinase 1; IRAK; IRAK-1; IRAK1; IRAK1_HUMAN; IRAK2; mPLK; OTTHUMP00000026014; OTTHUMP00000026015; OTTHUMP00000026020; OTTHUMP00000180621; Pelle; Pelle homolog; Pelle-like protein kinase; Plpk; IRAK-1; Pelle homolog; OTTHUMP00000026014; OTTHUMP00000026015; OTTHUMP00000026020; OTTHUMP00000180621;
Activated TLR4 signalling, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem;
ATP binding; NF-kappaB-inducing kinase activity; interleukin-1 receptor binding; kinase activity; nucleotide binding;
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