Recombinant Human Flavin Containing Monooxygenase 3

• Cat.No.: FMO3-718H

Specification

• Cat. No.: FMO3-718H
• Description: Dimethylaniline monooxygenase [N-oxide-forming] 3 is an enzyme that in humans is encoded by the FMO3 gene.
• Source: baculovirus infected insect cells.
• Biochem/physiol Actions: The FMO′s are responsible for catalyzing the oxygenation of a variety of xenobiotic and drug compounds including environmental pollutants and carcinogens which contain a nucleophilic nitrogen, sulfur, selenium, or phosphorus-containing moiety associated with their respective oxides. These enzymes are classified as Phase I or oxidative drug metabolism enzymes.
• Application: FMO3 is the major human hepatic form.
• Physical Form: Solution in 100 mM potassium phosphate buffer, pH 7.4.
• Form: buffered aqueous solution.
• Storage Temp: -70°C.

Gene Information

• Gene Name: FMO3 flavin containing monooxygenase 3 [ Homo sapiens ]
• Synonyms: flavin containing monooxygenase 3; TMAU; FMOII; MGC34400; dJ127D3.1; FMO3; dimethylaniline monooxygenase [N-oxide-forming] 3; FMO 3; FMO II; FMO form 2; dimethylaniline oxidase 3; hepatic flavin-containing monooxygenase 3; hepatic flavin-containing monooxygenase-3;Dimethylaniline oxidase 3; Hepatic flavin-containing monooxygenase 3; EC 1.14.13.8
• Gene ID: 2328
• mRNA Refseq: NM_001002294
• Protein Refseq: NP_001002294
• MIM: 136132
• UniProt ID: P31513
• Chromosome Location: 1q23-q25
• Pathway: Drug metabolism - cytochrome P450; Biological oxidations
• Function: FAD binding; NADP or NADPH binding; amino acid binding; flavin-containing monooxygenase activity; monooxygenase activity