Catalog # or name ...
Mouse Polyclonal antibody to Human METAP2.
This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2.
Full length Human Methionine Aminopeptidase 2, amino acids 1-478
Protein A purified
Preservative: NoneConstituents: 1X PBS, pH 7.2
Shipped at 4oC. Upon delivery aliquot and store at -20oC or -80oC. Avoid repeated freeze / thaw cycles.
Belongs to the peptidase M24A family.
Antigen Gene Information
METAP2 methionyl aminopeptidase 2 [ Homo sapiens ]
METAP2; methionyl aminopeptidase 2; methionine aminopeptidase 2; MAP2; MNPEP; p67; Peptidase M; AI047573; AL024412; AU014659,; MGC102452; A930035J23Rik; Amp2; AMPM2_HUMAN; EIF 2 associated p67 homolog; EIF-2-associated p67; Initiation factor 2 associated 67 kDa glycoprotein; Initiation factor 2-associated 67 kDa glycoprotein; MAP 2; MAP2; METAP 2; METAP2; Methionine aminopeptidase 2; Methionyl aminopeptidase 2; MGC127390; MGC53792; MNPEP; p67; p67eIF2; Peptidase M 2; Peptidase M2; MAP 2; metAP 2; peptidase M 2; eIF-2-associated p67 homolog; initiation factor 2-associated 67 kDa glycoprotein; p67eIF2;
aminopeptidase activity; metal ion binding; metalloexopeptidase activity; peptidase activity;
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