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Cat.No.
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CPBT-41699RH
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Product Overview
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Rabbit Polyclonal antibody to Human NNMT.
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Antigen Description
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N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor.
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Isotype
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IgG
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Immunogen
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This information is considered to be commercially sensitive
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Host
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Rabbit
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Species
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Human
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Specificity
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Predominantly expressed in the liver. A lower expression is seen in the kidney, lung, skeletal muscle, placenta and heart. Not detected in the brain or pancreas.
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Formulation
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Liquid
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Purity Detail
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Ammonium Sulphate Precipitation
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Applications
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ELISA, IHC-P
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Storage buffer
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Preservative: 0.09% Sodium AzideConstituents: PBS
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Storage
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Store at +4oC short term (1-2 weeks). Aliquot and store at -20oC or -80oC. Avoid repeated freeze / thaw cycles.
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Sequence similarities
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Belongs to the NNMT/PNMT/TEMT family.
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Antigen Gene Information
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Gene Name
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NNMT nicotinamide N-methyltransferase [ Homo sapiens ]
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Official Symbol
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NNMT
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Synonyms
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NNMT; nicotinamide N-methyltransferase; EC 2.1.1.1; Nicotinamide N methyltransferase; Nicotinamide N-methyltransferase; NNMT; NNMT_HUMAN;
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GeneID
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4837
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mRNA Refseq
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NM_006169
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Protein Refseq
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NP_006160
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MIM
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600008
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Uniprot ID
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P40261
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Chromosome Location
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11q23.1
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Pathway
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Biological oxidations, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Methylation, organism-specific biosystem; Nicotinate and nicotinamide metabolism, organism-specific biosystem;
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Function
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methyltransferase activity; nicotinamide N-methyltransferase activity; transferase activity;
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Download Datasheet:
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