|
Cat.No.
|
CPBT-42187RH
|
|
Product Overview
|
Rabbit Polyclonal antibody to Human P2RX5.
|
|
Antigen Description
|
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream gene, TAX1BP3 (Tax1 binding protein 3).
|
|
Isotype
|
IgG
|
|
Immunogen
|
Synthetic peptide from the cytoplasmic domain of Human P2X5b conjugated to an immunogenic carrier protein.
|
|
Host
|
Rabbit
|
|
Species
|
Human
|
|
Specificity
|
Expressed at high levels in brain and immune system.
|
|
Formulation
|
Liquid
|
|
Purity Detail
|
Whole antiserum
|
|
Applications
|
WB, IHC-P, IHC-Fr
|
|
Storage buffer
|
Preservative: NoneConstituents: Whole serum
|
|
Storage
|
Store at +4oC short term (1-2 weeks). Aliquot and store at -20oC (add glycerol to a final volume of 40% for extra stability). Avoid repeated freeze / thaw cycles.
|
|
Sequence similarities
|
Belongs to the P2X receptor family.
|
|
Antigen Gene Information
|
|
Gene Name
|
P2RX5 purinergic receptor P2X, ligand-gated ion channel, 5 [ Homo sapiens ]
|
|
Official Symbol
|
P2RX5
|
|
Synonyms
|
P2RX5; purinergic receptor P2X, ligand-gated ion channel, 5; P2X purinoceptor 5; P2X5; ATP receptor; ATP receptor subunit; Ionotropic ATP receptor P2X5; LRH 1; LRH1; Lymphoid restricted histocompatibility antigen 1; MGC47755; P2rx5; P2RX5_HUMAN; P2X purinoceptor 5; P2X5; P2X5R; Purinergic receptor; Purinergic receptor P2X ligand gated ion channel 5; Purinergic receptor P2X5; ATP receptor subunit; ionotropic ATP receptor P2X5; lymphoid-restricted histocompatibility antigen-1; LRH-1; P2X5R;
|
|
GeneID
|
5026
|
|
mRNA Refseq
|
NM_001204519
|
|
Protein Refseq
|
NP_001191448
|
|
MIM
|
602836
|
|
Uniprot ID
|
Q93086
|
|
Chromosome Location
|
17p13.3
|
|
Pathway
|
Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
|
|
Function
|
ATP binding; extracellular ATP-gated cation channel activity; extracellular ATP-gated cation channel activity; ion channel activity; purinergic nucleotide receptor activity;
|
|
|
|
Download Datasheet:
|
|