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Recombinant Human AXL protein(Met1-Pro449), His-tagged

Cat.No. : AXL-769H
Product Overview : Recombinant Human AXL isoform 1 (AAB20305.1) extracellular domain (Met1-Pro449) was expressed in HEK293, fused with a polyhistidine tag at the C-terminus.
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Source : HEK293
Species : Human
Tag : C-His
Protein length : Met1-Pro449
Form : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Molecular Mass : The secreted recombinant human AXL consists of 428 amino acids after removal of the signal peptide and predicts a molecular mass of 46.5 kDa. In SDS-PAGE under reducing conditions, it migRates as an approximately 60-70 kDa band due to glycosylation.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 98 % as determined by SDS-PAGE. > 90 % as determined by SEC-HPLC.
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Publication :
Efficacy of newly discovered DNA aptamers targeting AXL in a lung cancer cell with acquired resistance to Erlotinib (2021)
Harnessing MerTK agonism for targeted therapeutics (2020)
Conversion of RNA Aptamer into Modified DNA Aptamers Provides for Prolonged Stability and Enhanced Antitumor Activity (2021)
Gene Name : AXL AXL receptor tyrosine kinase [ Homo sapiens ]
Official Symbol : AXL
Synonyms : AXL; AXL receptor tyrosine kinase; tyrosine-protein kinase receptor UFO; JTK11; UFO; AXL oncogene; oncogene AXL; AXL transforming sequence/gene;
Gene ID : 558
mRNA Refseq : NM_001699
Protein Refseq : NP_001690
MIM : 109135
UniProt ID : P30530

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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