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Recombinant Human Secretory Leukocyte Peptidase Inhibitor, His-tagged

Cat.No. : SLPI-2575H
Product Overview : Recombinant human SLPI, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography. MW = 14.0kDa (128aa).
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Cat. No. : SLPI-2575H
Description : SLPI is a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes; the protein is also thought to have broad-spectrum anti-biotic activity.
Source : E.coli.
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MSGKSFKAGV CPPKKSAQCL RYKKPECQSD WQCPGKKRCC PDTCGIKCLD PVDTPNPTRR KPGKCPVTYG QCLMLNPPNF CEMDGQCKRD LKCCMGMCGK SCVSPVKA
Purity : > 80% by SDS – PAGE.
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 2mM DTT, 100mM NaCl.
Concentration : 0.5 mg/ml (determined by Bradford assay).
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : SLPI secretory leukocyte peptidase inhibitor [ Homo sapiens ]
Synonyms : SLPI; secretory leukocyte peptidase inhibitor; ALP; MPI; ALK1; BLPI; HUSI; WAP4; WFDC4; HUSI-I; antileukoproteinase; HUSI-1; protease inhibitor WAP4; mucus proteinase inhibitor; seminal proteinase inhibitor; WAP four-disulfide core domain 4; WAP four-disulfide core domain protein 4; secretory leukocyte protease inhibitor (antileukoproteinase);Secretory leukocyte protease inhibitor
Gene ID : 6590
mRNA Refseq : NM_003064
Protein Refseq : NP_003055
MIM : 107285
UniProt ID : P03973
Chromosome Location : 20q12
Function : endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any side effects associated with the use of SLPI protein in clinical applications? 12/15/2022

The potential side effects of SLPI supplementation or therapy have not been extensively studied and would require further investigation.

Are there any clinical trials using SLPI protein for the treatment of inflammatory conditions? 07/21/2022

Several clinical trials have investigated the use of SLPI in conditions such as chronic obstructive pulmonary disease (COPD) and inflammatory bowel disease (IBD).

Are there any diagnostic applications of SLPI protein? 02/08/2019

SLPI levels in biological fluids, such as saliva and sputum, have been studied as potential biomarkers for various diseases and conditions.

How does SLPI protein affect inflammation? 07/28/2017

SLPI has anti-inflammatory properties and can inhibit the activity of various proteases involved in the inflammatory response.

How is SLPI protein being studied in the context of HIV/AIDS? 01/07/2017

SLPI has been investigated as a potential therapeutic agent for HIV/AIDS, as it may inhibit viral replication and transmission.

Customer Reviews (3)

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Reviews
12/06/2022

    the SLPI protein is highly regarded for its excellent performance in WB assays and its significant contribution to protein EM structure analysis.

    02/27/2021

      The SLPI protein is highly recommended for researchers conducting protein studies, especially in Western blotting (WB) experiments.

      10/25/2016

        Its reliability and high quality make it a valuable tool in various applications, ranging from enzymatic assays to studying protein-protein interactions.

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