Recombinant Human Secretory Leukocyte Peptidase Inhibitor, His-tagged
Cat.No. : | SLPI-2575H |
Product Overview : | Recombinant human SLPI, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography. MW = 14.0kDa (128aa). |
- Specification
- Gene Information
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Cat. No. : | SLPI-2575H |
Description : | SLPI is a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes; the protein is also thought to have broad-spectrum anti-biotic activity. |
Source : | E.coli. |
Sequences Of Amino Acids : | MGSSHHHHHH SSGLVPRGSH MSGKSFKAGV CPPKKSAQCL RYKKPECQSD WQCPGKKRCC PDTCGIKCLD PVDTPNPTRR KPGKCPVTYG QCLMLNPPNF CEMDGQCKRD LKCCMGMCGK SCVSPVKA |
Purity : | > 80% by SDS – PAGE. |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 2mM DTT, 100mM NaCl. |
Concentration : | 0.5 mg/ml (determined by Bradford assay). |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | SLPI secretory leukocyte peptidase inhibitor [ Homo sapiens ] |
Synonyms : | SLPI; secretory leukocyte peptidase inhibitor; ALP; MPI; ALK1; BLPI; HUSI; WAP4; WFDC4; HUSI-I; antileukoproteinase; HUSI-1; protease inhibitor WAP4; mucus proteinase inhibitor; seminal proteinase inhibitor; WAP four-disulfide core domain 4; WAP four-disulfide core domain protein 4; secretory leukocyte protease inhibitor (antileukoproteinase);Secretory leukocyte protease inhibitor |
Gene ID : | 6590 |
mRNA Refseq : | NM_003064 |
Protein Refseq : | NP_003055 |
MIM : | 107285 |
UniProt ID : | P03973 |
Chromosome Location : | 20q12 |
Function : | endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity |
Products Types
◆ Recombinant Protein | ||
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Slpi-5945M | Recombinant Mouse Slpi Protein, Myc/DDK-tagged | +Inquiry |
SLPI-2704H | Recombinant Human SLPI Protein, His-tagged | +Inquiry |
SLPI-2036H | Recombinant Human SLPI Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SLPI-530HCL | Recombinant Human SLPI cell lysate | +Inquiry |
SLPI-001HCL | Recombinant Human SLPI cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionThe potential side effects of SLPI supplementation or therapy have not been extensively studied and would require further investigation.
Several clinical trials have investigated the use of SLPI in conditions such as chronic obstructive pulmonary disease (COPD) and inflammatory bowel disease (IBD).
SLPI levels in biological fluids, such as saliva and sputum, have been studied as potential biomarkers for various diseases and conditions.
SLPI has anti-inflammatory properties and can inhibit the activity of various proteases involved in the inflammatory response.
SLPI has been investigated as a potential therapeutic agent for HIV/AIDS, as it may inhibit viral replication and transmission.
Customer Reviews (3)
Write a reviewthe SLPI protein is highly regarded for its excellent performance in WB assays and its significant contribution to protein EM structure analysis.
The SLPI protein is highly recommended for researchers conducting protein studies, especially in Western blotting (WB) experiments.
Its reliability and high quality make it a valuable tool in various applications, ranging from enzymatic assays to studying protein-protein interactions.
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