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Recombinant Human PSMB5, 60-263 aa, His-tagged

Cat.No. : PSMB5-3374H
Product Overview : Recombinant human PSMB5 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques.MW = 26.7 kDa (241aa).
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  • Gene Information
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Cat. No. : PSMB5-3374H
Description : PSMB5 is a member of the proteasome B-type family that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). PSMB5 has an ATP dependent proteolytic activity and involved in an ATP/ubiquitin dependent non lysosomal proteolytic pathway.
Source : E.coli.
Form : Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 20% glycerol 5mM DTT, 0.2M NaCl.
Purity : > 90% by SDS - PAGE.
Concentration : 0.25 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMTTT LAFKFRHGVI VAADSRATAG AYIASQTVKK VIEINPYLLG TMAGGAADCS FWERLLARQC RIYELRNKER ISVAAASKLL ANMVYQYKGM GLSMGTMICG WDKRGPGLYY VDSEGNRISG ATFSVGSGSV YAYGVMDRGY SYDLEVEQAY DLARRAIYQA TYRDAYSGGA VNLYHVREDG WIRVSSDNVA DLHEKYSGST P.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways : Proteasome; Apoptosis; Cell Cycle Checkpoints; Cell Cycle, Mitotic; DNA Replication; HIV Infection; Metabolism of amino acids and derivatives; Signaling by Wnt
Gene Name : PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 [ Homo sapiens ]
Synonyms : proteasome (prosome, macropain) subunit, beta type, 5; X; MB1; LMPX; MGC104214; PSMB5; proteasome subunit beta type-5; proteasome chain 6; proteasome subunit X; proteasome subunit MB1; macropain epsilon chain; proteasome epsilon chain; proteasome beta 5 subunit; proteasome catalytic subunit 3; proteasome subunit, beta type, 5; PSX large multifunctional protease X; multicatalytic endopeptidase complex epsilon chain; Multicatalytic endopeptidase complex epsilon chain; Proteasome epsilon chain; Proteasome subunit X; Proteasome chain 6; Proteasome subunit MB1; Macropain epsilon chain
Gene ID : 5693
mRNA Refseq : NM_001130725
Protein Refseq : NP_001124197
MIM : 600306
UniProt ID : P28074
Chromosome Location : 14q11.2
Function : peptidase activity;' protein binding; threonine-type endopeptidase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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