Recombinant Human PTPN1, His tagged
Cat.No. : | PTPN1-764H |
Product Overview : | Recombinant Human PTPN1 (NP_002818.1) (Glu 2 -Asn 321), fused with a polyhistide tag at the N-terminus, was produced in E. coli. |
- Specification
- Gene Information
- Related Products
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Lyophilized from sterile 10mM HEPES, 500mM NaCl, 1mM DTT, 1mM EDTA, pH 7.5 |
Molecular Mass : | The recombinant human PTPN1consisting of 327 amino acids and has a calculated molecular mass of 38 kDa. It migrates as an approximately 36 kDa band in SDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70oC. |
Storage : | Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | PTPN1 protein tyrosine phosphatase, non-receptor type 1 [ Homo sapiens ] |
Official Symbol : | PTPN1 |
Gene ID : | 5770 |
mRNA Refseq : | NM_002827 |
Protein Refseq : | NP_002818 |
MIM : | 176885 |
UniProt ID : | P18031 |
Products Types
◆ Recombinant Protein | ||
PTPN1-32H | Recombinant Human PTPN1 Protein | +Inquiry |
PTPN1-081H | Recombinant Human PTPN1 Protein | +Inquiry |
Ptpn1-5234M | Recombinant Mouse Ptpn1 Protein, Myc/DDK-tagged | +Inquiry |
PTPN1-7275M | Recombinant Mouse PTPN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PTPN1-3521R | Recombinant Rhesus Macaque PTPN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PTPN1-2686HCL | Recombinant Human PTPN1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionAltered PTPN1 activity is associated with obesity, as it impacts pathways involved in energy balance and fat storage.
Genetic variations in PTPN1 can affect its activity and thereby influence metabolic processes and disease risk.
PTPN1 is implicated in insulin resistance, potentially contributing to the development of type 2 diabetes.
It negatively regulates insulin signaling by dephosphorylating insulin receptor substrates, affecting glucose uptake and metabolism.
PTPN1 interacts with various signaling proteins, playing a role in diverse metabolic pathways including lipid and glucose metabolism.
PTPN1, also known as Protein Tyrosine Phosphatase Non-Receptor Type 1, is key in dephosphorylating proteins involved in signal transduction.
Targeting PTPN1 could offer therapeutic benefits in treating insulin resistance, type 2 diabetes, and obesity.
Customer Reviews (3)
Write a reviewTimely and precise. Essential for achieving research goals.
Efficient service, valuable insights. Key to research success.
Saves time and resources. Critical for our research.
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