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Cat.No.
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CPBT-44985RH
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Product Overview
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Rabbit Polyclonal antibody to Human SEC61B.
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Antigen Description
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The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.
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Isotype
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IgG
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Immunogen
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Synthetic peptide conjugated to KLH corresponding to amino acids 2-10 of human SEC61b (PGPTPSGTN-C) containing a C terminal cysteine.
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Host
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Rabbit
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Species
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Human
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Formulation
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Liquid
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Purity Detail
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Whole antiserum
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Applications
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WB, AP
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Storage buffer
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Preservative: 0.05% Sodium AzideConstituents: 30% Glycerol
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Storage
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Shipped at 4oC. Upon delivery aliquot and store at -20oC or -80oC. Avoid repeated freeze / thaw cycles.
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Antigen Gene Information
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Gene Name
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SEC61B Sec61 beta subunit [ Homo sapiens ]
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Official Symbol
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SEC61B
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Synonyms
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SEC61B; Sec61 beta subunit; protein transport protein Sec61 subunit beta; Protein translocation complex beta; Protein transport protein SEC61 beta subunit; Protein transport protein Sec61 subunit beta; SEC 61B; SEC61 B; Sec61 beta subunit; Sec61 complex beta subunit; Sec61 complex, beta subunit; protein translocation complex beta; protein transport protein SEC61 beta subunit;
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GeneID
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10952
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mRNA Refseq
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NM_006808
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Protein Refseq
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NP_006799
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MIM
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609214
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Uniprot ID
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P60468
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Chromosome Location
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9q22.32-q31.3
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Pathway
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Adaptive Immune System, organism-specific biosystem; Antigen processing-Cross presentation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Diabetes pathways, organism-specific biosystem;
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Function
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epidermal growth factor binding; protein binding;
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Download Datasheet:
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