Recombinant Human S100 Calcium Binding Protein Z, His-tagged

• Cat.No.: S100Z-2581H
• Product Overview: Recombinant human S100Z, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques.

Specification

• Cat. No.: S100Z-2581H
• Description: S100 calcium binding protein Z, also known as S100Z, is member of the S100 protein family. S100 proteins are small dimeric members of the EF-hand superfamily of Ca(2+) binding proteins thought to participate in mediating intracellular Ca(2+) signals by binding to and thereby regulating target proteins in a Ca(2+)-dependent manner. There are differences in the expression level of S100Z mRNA in various tissues. The highest levels were found in spleen and leukocytes.S100Z gene expression appears to be deregulated in some tumor tissues, compared to expression in their normal counterparts. Recombinant human S100Z, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Source: E.coli.
• Sequences: MGSSHHHHHH SSGLVPRGSH MPTQLEMAMD TMIRIFHRYS GKERKRFKLS KGELKLLLQR ELTEFLSCQK ETQLVDKIVQ DLDANKDNEV DFNEFVVMVA ALTVACNDYF VEQLKKKGK.
• Molecular Weight: 13.7 kDa (119aa), confirmed by MALDI-TOF.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 1mM EDTA, 50mM NaCl.
• Purity: > 95% by SDS – PAGE.
• Concentration: 1mg/ml (determined by Bradford assay).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: S100Z S100 calcium binding protein Z [ Homo sapiens ]
• Synonyms:
  S100Z; S100 calcium binding protein Z; Gm625; S100-zeta; protein S100-Z; S100 calcium-binding protein Z; protein S100-Z; S100 calcium binding protein, zeta
• Gene ID: 170591
• mRNA Refseq: NM_130772
• Protein Refseq: NP_570128
• MIM: 610103
• UniProt ID: Q8WXG8
• Chromosome Location: 5q13.3
• Function: calcium ion binding