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Recombinant Human TGM2 protein, His-tagged

Cat.No. : TGM2-922H
Product Overview : Recombinant Human TGM2 protein(NP_004604.2)(Met1-Ala687), fused with His tag, was expressed in Insect Cells.
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Source : Insect Cells
Species : Human
Tag : His
Form : Lyophilized from sterile 50mM Tris, 100mM NaCl, 2mM DTT, 10% glycerol, pH 8.0Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Molecular Mass : The recombinant human TGM2 consists of 705 amino acids and has a predicted molecular mass of 79.6 kDa. It migrates as an approximately 80 kDa band in SDS-PAGE under reducing conditions as estimated.
Protein Length : Met1-Ala687
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 97 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : TGM2 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) [ Homo sapiens ]
Official Symbol : TGM2
Synonyms : TGM2; transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase); protein-glutamine gamma-glutamyltransferase 2; TGC; TG(C); TGase C; TGase H; TGase-2; TGase-H; C polypeptide; transglutaminase C; transglutaminase H; transglutaminase-2; tissue transglutaminase; protein-glutamine-gamma-glutamyltransferase; TG2; GNAH; G-ALPHA-h;
Gene ID : 7052
mRNA Refseq : NM_004613
Protein Refseq : NP_004604
MIM : 190196
UniProt ID : P21980

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there diagnostic applications of TGM2 in clinical settings? 02/28/2021

TGM2 levels and activity can serve as diagnostic markers in certain conditions, providing insights into the progression and severity of diseases.

How does TGM2 influence cardiovascular health? 01/26/2021

TGM2 has been associated with cardiovascular diseases, contributing to the development of atherosclerosis and vascular calcification.

How does TGM2 contribute to fibrosis in organ tissues? 10/25/2020

TGM2 plays a role in fibrosis by promoting the cross-linking of extracellular matrix proteins, contributing to tissue stiffness and impaired organ function.

How does TGM2 affect inflammation and immune responses? 09/17/2020

TGM2 is involved in modulating inflammation and immune responses, influencing processes such as cytokine production and leukocyte adhesion.

Are there genetic mutations related to TGM2 that impact clinical outcomes? 07/08/2017

Genetic variations in TGM2 have been identified, and certain mutations may influence susceptibility to specific diseases or alter the enzyme's functionality.

Customer Reviews (3)

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12/21/2020

    The TGM2 protein has demonstrated its efficacy in protein electron microscopy structure analysis.

    03/30/2020

      Whether utilized in protein-protein interaction studies or enzymatic assays, this protein exhibits robust performance, enabling accurate data generation and analysis.

      07/19/2018

        This cutting-edge technique allows for the visualization and characterization of protein structures at the atomic level, providing insights into their function and potential therapeutic targets.

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