Catalog # or name ...
Rabbit Polyclonal antibody to Human SP3.
This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13.
Synthetic peptide from within residues: AGINADGHLI NTGQAMDSSD NSERTGERVS PDINETNTDT DLFVPTSSSS, corresponding to internal sequence amino acids 288-337 of Human SP3.
Immunogen affinity purified
Preservative: NoneConstituents: 2% Sucrose, PBS
Shipped at 4oC. Upon delivery aliquot and store at -20oC. Avoid repeated freeze / thaw cycles.
Belongs to the Sp1 C2H2-type zinc-finger protein family.Contains 3 C2H2-type zinc fingers.
Antigen Gene Information
SP3 Sp3 transcription factor [ Homo sapiens ]
SP3; Sp3 transcription factor; transcription factor Sp3; SPR 2; D130027J01Rik; DKFZp686O1631; GC binding transcription factor Sp 3; GC binding transcription factor Sp3; MGC105187; OTTMUSP00000014207; SP 3; Sp 3 transcription factor; SP3; Sp3 transcription factor; SP3_HUMAN; Specificity protein 3; SPR 2; SPR-2; SPR2; Transcription factor SP 3; Transcription factor SP3; OTTHUMP00000163171; OTTHUMP00000205122; OTTHUMP00000220849; specificity protein 3; GC-binding transcription factor Sp3; SPR2;
Regulation of Telomerase, organism-specific biosystem; Selenium Metabolism and Selenoproteins, organism-specific biosystem;
DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; chromatin binding; double-stranded DNA binding; metal ion binding;
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