Catalog # or name ...
Mouse Polyclonal antibody to Human SNRPN.
The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5 untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5 UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure.
SNRPN (AAH03180, 1 a.a. ~ 241 a.a) full-length human protein.
Protein A purified
Preservative: NoneConstituents: PBS, pH 7.2
Shipped at 4oC. Upon delivery aliquot and store at -20oC or -80oC. Avoid repeated freeze / thaw cycles.
Antigen Gene Information
SNRPN small nuclear ribonucleoprotein polypeptide N [ Homo sapiens ]
SNRPN; small nuclear ribonucleoprotein polypeptide N; Prader Willi syndrome chromosome region , PWCR; small nuclear ribonucleoprotein-associated protein N; HCERN3; RT LI; SM protein N; SM D; small nuclear ribonucleoprotein N; SMN; SNRNP N; SNURF SNRPN; tissue specific splicing protein; HCERN3; RT LI; RTLI; SM D; Sm N; Sm protein N; Small nuclear ribonucleoprotein associated protein N; Small nuclear ribonucleoprotein polypeptide N; SMD; SMN; SNRNP N; SNRNPN; SNURF SNRPN; Tissue specific splicing protein; sm protein D; tissue-specific splicing protein; tissue-specific-splicing protein; PWCR; SM-D; sm-N; RT-LI; SNRNP-N; SNURF-SNRPN;
mRNA processing, organism-specific biosystem;
RNA binding; protein binding;
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