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Recombinant Human Interferon Gamma

Cat.No. : IFNG-94H
Product Overview : Recombinant HumanIFNG protein (Met 1 - Gln 166) was expressed inCHO Cells.
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  • Gene Information
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Cat. No. : IFNG-94H
Description : Interferon gamma, also known as IFN-gamma, Immune interferon and IFNG, is a secreted protein which belongs to the type II (or gamma) interferon family. IFN-gamma / IFNG is produced by lymphocytes and activated by specific antigens or mitogens. IFN-gamma / IFNG, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Source : CHO Cells.
Molecular Mass : The secreted recombinant human γ-IFN consists of 143 amino acids and has a predicted molecular mass of 16.7 kDa. γ-IFN migrates as two bands with apparent molecular mass of 21&25 kDa probably due to different glycosylation.
Predicted N Terminal : Gln 24.
Purity : > 92 %.
Formulation : Lyophilized from sterile PBS, pH 7.4.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution : A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Storage And Stability : Samples are stable for up to twelve months from date of receipt at -700C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Gene Name : IFNG interferon, gamma [ Homo sapiens ]
Synonyms : IFG; IFI;Immune interferon, type II interferon; T cell interferon; MAF; IFN-gamma; Interferongamma; Interferon gamma precursor; interferon gamma; IFNG; interferon, gamma
Gene ID : 3458
mRNA Refseq : NM_000619
Protein Refseq : NP_000610
MIM : 147570
UniProt ID : P01579
Chromosome Location : 12q14
Pathway : Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Natural killer cell mediated cytotoxicity; Regulation of autophagy; T cell receptor signaling pathway; TGF-beta signaling pathway; Type I diabetes mellitus
Function : cytokine activity; interferon-gamma receptor binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the role of IFNG in tumor immunotherapy? 09/23/2022

IFNG plays an important role in tumor immunotherapy, which can activate the immune response of tumor cells, promote apoptosis of tumor cells and inhibit the proliferation of tumor cells.

What is the current progress in drug development for IFNG? 12/19/2021

The development of drugs for IFNG is currently in clinical trials, including monoclonal antibodies against IFNG receptors and inhibitors against IFNG signaling pathways.

How is IFNG related to muscle wasting? 12/02/2021

Studies have shown that IFNG can inhibit the occurrence of muscle atrophy, but the specific mechanism is not clear.

How can IFNG be used as a biomarker in clinical practice? 03/01/2021

In clinical practice, the expression level of IFNG can be measured to predict the progression and prognosis of the disease, and to guide the choice of treatment regimen.

Are there other coding variants in the IFNG gene? 07/12/2020

Yes, there are other coding variants in the IFNG gene that may have different functions and expression patterns.

Is the expression of IFNG affected by environmental factors? 05/26/2020

Such as nutritional status, inflammation levels, etc. Yes, the expression of IFNG is affected by environmental factors, such as nutritional status, inflammation level, etc.

Customer Reviews (3)

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Reviews
12/17/2022

    It is analyzed by X-ray crystallography or other crystallization techniques and has good crystallization properties.

    06/10/2022

      Easy to attach to the surface of cells or materials.

      04/02/2022

        IFNG products have a complete range of specifications for experimental designs of different sizes and needs.

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