Recombinant Human Interferon Gamma
Cat.No. : | IFNG-94H |
Product Overview : | Recombinant HumanIFNG protein (Met 1 - Gln 166) was expressed inCHO Cells. |
- Specification
- Gene Information
- Related Products
Cat. No. : | IFNG-94H |
Description : | Interferon gamma, also known as IFN-gamma, Immune interferon and IFNG, is a secreted protein which belongs to the type II (or gamma) interferon family. IFN-gamma / IFNG is produced by lymphocytes and activated by specific antigens or mitogens. IFN-gamma / IFNG, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. |
Source : | CHO Cells. |
Molecular Mass : | The secreted recombinant human γ-IFN consists of 143 amino acids and has a predicted molecular mass of 16.7 kDa. γ-IFN migrates as two bands with apparent molecular mass of 21&25 kDa probably due to different glycosylation. |
Predicted N Terminal : | Gln 24. |
Purity : | > 92 %. |
Formulation : | Lyophilized from sterile PBS, pH 7.4. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Reconstitution : | A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. |
Storage And Stability : | Samples are stable for up to twelve months from date of receipt at -700C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Gene Name : | IFNG interferon, gamma [ Homo sapiens ] |
Synonyms : | IFG; IFI;Immune interferon, type II interferon; T cell interferon; MAF; IFN-gamma; Interferongamma; Interferon gamma precursor; interferon gamma; IFNG; interferon, gamma |
Gene ID : | 3458 |
mRNA Refseq : | NM_000619 |
Protein Refseq : | NP_000610 |
MIM : | 147570 |
UniProt ID : | P01579 |
Chromosome Location : | 12q14 |
Pathway : | Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Natural killer cell mediated cytotoxicity; Regulation of autophagy; T cell receptor signaling pathway; TGF-beta signaling pathway; Type I diabetes mellitus |
Function : | cytokine activity; interferon-gamma receptor binding |
Products Types
◆ Recombinant Protein | ||
IFNG-117R | Recombinant Rat IFNG Protein | +Inquiry |
IFNG-1184H | Recombinant Human IFNG Protein, MYC/DDK-tagged | +Inquiry |
IFNG-8549H | Active Recombinant Human IFNG protein(Met1-Gln166) | +Inquiry |
IFNG-359C | Recombinant Cynomolgus Monkey IFNG Protein, His (Fc)-Avi-tagged | +Inquiry |
Ifng-379I | Active Recombinant Mouse Ifng Protein (134 aa) | +Inquiry |
◆ Lysates | ||
IFNG-1797MCL | Recombinant Mouse IFNG cell lysate | +Inquiry |
IFNG-001HCL | Recombinant Human IFNG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionIFNG plays an important role in tumor immunotherapy, which can activate the immune response of tumor cells, promote apoptosis of tumor cells and inhibit the proliferation of tumor cells.
The development of drugs for IFNG is currently in clinical trials, including monoclonal antibodies against IFNG receptors and inhibitors against IFNG signaling pathways.
Studies have shown that IFNG can inhibit the occurrence of muscle atrophy, but the specific mechanism is not clear.
In clinical practice, the expression level of IFNG can be measured to predict the progression and prognosis of the disease, and to guide the choice of treatment regimen.
Yes, there are other coding variants in the IFNG gene that may have different functions and expression patterns.
Such as nutritional status, inflammation levels, etc. Yes, the expression of IFNG is affected by environmental factors, such as nutritional status, inflammation level, etc.
Customer Reviews (3)
Write a reviewIt is analyzed by X-ray crystallography or other crystallization techniques and has good crystallization properties.
Easy to attach to the surface of cells or materials.
IFNG products have a complete range of specifications for experimental designs of different sizes and needs.
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