Recombinant Human N-acetylneuraminic Acid Synthase, His-tagged
Cat.No. : | NANS-2867H |
Product Overview : | Recombinant human NANS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW = 42.4 kDa (379aa) confirmed by MALDI-TOF. |
- Specification
- Gene Information
- Related Products
Cat. No. : | NANS-2867H |
Description : | NANS, also known as SAS, is a 359 amino acid protein that contains one AFP (antifreeze proteins)-like domain and functions in the biosynthesis of sialic acids. Expressed ubiquitously, NANS enzymatically catalyzes the H2O-dependent formation of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), both of which are sialic acids. NANS uses N-acetylmannosamine 6-phosphate as a substrate for Neu5Ac synthesis and mannose 6-phosphate as a substrate for KDN synthesis. |
Source : | E.coli. |
Sequences Of Amino Acids : | MGSSHHHHHH SSGLVPRGSH MPLELELCPG RWVGGQHPCF IIAEIGQNHQ GDLDVAKRMI RMAKECGADC AKFQKSELEF KFNRKALERP YTSKHSWGKT YGEHKRHLEF SHDQYRELQR YAEEVGIFFT ASGMDEMAVE FLHELNVPFF KVGSGDTNNF PYLEKTAKKG RPMVISSGMQ SMDTMKQVYQ IVKPLNPNFC FLQCTSAYPL QPEDVNLRVI SEYQKLFPDI PIGYSGHETG IAISVAAVAL GAKVLERHIT LDKTWKGSDH SASLEPGELA ELVRSVRLVE RALGSPTKQL LPCEMACNEK LGKSVVAKVK IPEGTILTMD MLTVKVGEPK GYPPEDIFNL VGKKVLVTVE EDDTIMEELV DNHGKKIKS |
Purity : | > 95% by SDS – PAGE. |
Form : | Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.1M NaCl, 1mM DTT, 10% glycerol. |
Concentration : | 0.5 mg/ml (determined by Bradford assay). |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | NANS N-acetylneuraminic acid synthase [ Homo sapiens ] |
Synonyms : | NANS; N-acetylneuraminic acid synthase; SAS; sialic acid synthase; N-acetylneuraminate synthase; sialic acid phosphate synthase; N-acetylneuraminate-9-phosphate synthase; N-acetylneuraminic acid phosphate synthase; EC 2.5.1.56; EC 2.5.1.57 |
Gene ID : | 54187 |
mRNA Refseq : | NM_018946 |
Protein Refseq : | NP_061819 |
MIM : | 605202 |
UniProt ID : | Q9NR45 |
Chromosome Location : | 9p24.1-p23 |
Pathway : | Amino sugar and nucleotide sugar metabolism; Metabolic pathways |
Function : | N-acetylneuraminate synthase activity; N-acylneuraminate cytidylyltransferase activity; N-acylneuraminate-9-phosphate synthase activity; transferase activity |
Products Types
◆ Recombinant Protein | ||
Nans-4288M | Recombinant Mouse Nans Protein, Myc/DDK-tagged | +Inquiry |
NANS-1477H | Recombinant Human NANS Protein, His (Fc)-Avi-tagged | +Inquiry |
NANS-4947H | Recombinant Human NANS Protein (Met1-Ser359), N-His tagged | +Inquiry |
NANS-28783TH | Recombinant Human NANS, His-tagged | +Inquiry |
NANS-1816C | Recombinant Chicken NANS | +Inquiry |
◆ Lysates | ||
NANS-3979HCL | Recombinant Human NANS 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket