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Recombinant Human Tec Protein Tyrosine Kinase, GST-tagged

Cat.No. : TEC-2621H
Product Overview : Recombinant Human TEC, catalytic domain [359-631 amino acids] was expressed as N-terminal GST-fusion protein (59 kDa) usingbaculovirusexpression system. GST-TEC was purified by using glutathione sepharose chromatography and anion exchange chromatography.
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  • Gene Information
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Cat. No. : TEC-2621H
Description : The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
Source : baculovirus.
Purity : 100%. The purity was assessed by SDS-PAGE/CBB staining.
Storage Buffer : 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5.
ATP : 100μM.
Substrate : Srctide.
Storage : Store at -80℃. Avoid repeating freeze-thaws.
Gene Name : TEC tec protein tyrosine kinase [ Homo sapiens ]
Synonyms : TEC; tec protein tyrosine kinase; PSCTK4; MGC126760; MGC126762; tyrosine-protein kinase Tec; EC 2.7.10.2
Gene ID : 7006
mRNA Refseq : NM_003215
Protein Refseq : NP_003206
MIM : 600583
UniProt ID : P42680
Chromosome Location : 4p12
Pathway : T cell receptor signaling pathway
Function : ATP binding; metal ion binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein binding; transferase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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