Recombinant Human Phosphoglycerate Mutase 1 (Brain), His-tagged
Cat.No. : | PGAM1-2786H |
Product Overview : | Recombinant human PGAM protein (1-254aa), fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PGAM1-2786H |
Description : | PGAM1 belongs to the phosphoglycerate mutase family. This protein is important components of glucose and 2,3-BPGA (2,3-bisphosphoglycerate) metabolism and catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). Mutations in this protein cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X. |
Source : | E.coli. |
Sequences : | MGSSHHHHHH SSGLVPRGSH MAAYKLVLIR HGESAWNLEN RFSGWYDADL SPAGHEEAKR GGQALRDAGY EFDICFTSVQ KRAIRTLWTV LDAIDQMWLP VVRTWRLNER HYGGLTGLNK AETAAKHGEA QVKIWRRSYD VPPPPMEPDH PFYSNISKDR RYADLTEDQL PSCESLKDTI ARALPFWNEE IVPQIKEGKR VLIAAHGNSL RGIVKHLEGL SEEAIMELNL PTGIPIVYEL DKNLKPIKPM QFLGDEETVR KAMEAVAAQG KAKK. |
Form : | Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.1M Nacl, 1mM DTT, 10% glycerol. |
Molecular Weight : | 30.9kDa (274aa), confirmed by MALDI-TOF. |
Purity : | > 90% by SDS – PAGE. |
Concentration : | 1 mg/ml (determined by Bradford assay). |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | PGAM1 phosphoglycerate mutase 1 (brain) [ Homo sapiens ] |
Synonyms : | PGAM1; phosphoglycerate mutase 1 (brain); BPG-dependent PGAM 1; phosphoglycerate mutase 1; phosphoglycerate mutase A, nonmuscle form; phosphoglycerate mutase isozyme B; EC 3.1.3.13; EC 5.4.2.1; EC 5.4.2.4 |
Gene ID : | 5223 |
mRNA Refseq : | NM_002629 |
Protein Refseq : | NP_002620 |
MIM : | 172250 |
UniProt ID : | P18669 |
Chromosome Location : | 10q25.3 |
Pathway : | Glycolysis / Gluconeogenesis; Metabolic pathways |
Function : | 2,3-bisphospho-D-glycerate 2-phosphohydrolase activity;bisphosphoglycerate mutase activity;hydrolase activity;isomerase activity;phosphoglycerate mutase activity; protein kinase binding |
Products Types
◆ Recombinant Protein | ||
PGAM1-0574H | Recombinant Human PGAM1 Protein (M1-K254), Tag Free | +Inquiry |
PGAM1-1656H | Recombinant Human PGAM1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PGAM1-3204R | Recombinant Rhesus Macaque PGAM1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PGAM1-0575H | Recombinant Human PGAM1 Protein (M1-K254), His/Strep tagged | +Inquiry |
PGAM1-4059R | Recombinant Rat PGAM1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PGAM1-3264HCL | Recombinant Human PGAM1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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