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Recombinant Human Interferon, Alpha 2

Cat.No. : IFNA2-91H
Product Overview : Recombinant Human Interferon, Alpha 2 was expressed inPseudomonas putida. MW = 19.2 kDa.
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  • Gene Information
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Cat. No. : IFNA2-91H
Description : Interferon-α (INF-α), also known as leukocyte interferon, comprises a grope of related but distinct proteins that share over 95 % amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, 100 kDa ligand-binding subunit (INF-αR1) and a 125 kDa subunit (INF-αR2) that is involved both in ligand binding and signal transduction. INF-α has both anti-viral and immunomodulatory activities on target cells.
Source : Pseudomonas putida.
Purity : >98% determined by HPLC and PAGE.
Form : lyophilised with carrier.
Sterilized : Yes.
Biological Activity : >2.5 x 10E+8 unit/mg was determined in the cytopathic effect inhibition assay using human diploid fibroblast cells with vesicular stomatitis virus (VSV). A cytopathic effect of 50% was produced with 1 unit/ml interferon. The units are determined according to the international reference standard provided by WHO.
Contaminations : protein <2% (HPLC), DNA <50pg/mg of protein.
Storage : -70°C.
Gene Name : IFNA2 interferon, alpha 2 [ Homo sapiens ]
Synonyms : IFNA2; interferon, alpha 2; Interferon, alpha-2;; IFNA; INFA2; MGC125764; MGC125765; Interferon alpha A; Alpha-2a interferon; Interferon alpha 2b; OTTHUMP00000021143; Interferon alpha-A; LeIF A
Gene ID : 3440
mRNA Refseq : NM_000605
Protein Refseq : NP_000596
MIM : 147562
UniProt ID : P01563
Chromosome Location : 9p22
Pathway : Antigen processing and presentation; Autoimmune thyroid disease; Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Natural killer cell mediated cytotoxicity; RIG-I-like receptor signaling pathway; Regulation of autophagy; Toll-like receptor signaling pathway
Function : cytokine activity; interferon-alpha/beta receptor binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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