Recombinant Human IKBKE, GST-His

• Cat.No.: IKBKE-2662H
• Product Overview: Recombinant Human IKBKE, full length, amino acids M1-V716, N-terminal GST-HIS6 fusion protein with a Thrombin cleavage site, expressed inSf9 insect cells.

Specification

• Cat. No.: IKBKE-2662H
• Description: Inhibitor of nuclear factor kappa-B kinase subunit epsilon is an enzyme that in humans is encoded by the IKBKE gene.
• Source: Sf9 insect cells.
• Purification: Immobilized Metal Affinity Chromatography.
• Product Identity: IKK-epsilon was confirmed as IKK-epsilon by mass spectroscopy LC-ESI-MS/MS.
• MW: 110,059 Da.
• Storage Buffer: 50 mM Tris-HCl, pH 7.5; 100 mM NaCl, 5 mM DTT, 20% glycerol.
• Concentration: 0.055 μg/μl.
• Specific Activity: 42 pmol/μg×min.
• Storage: -80°C. Avoid repeated freeze-thaw cycles!

Gene Information

• Gene Name: IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon [ Homo sapiens ]
• Synonyms:
  IKBKE; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon; I-kappa-B kinase epsilon; IKK-epsilon; IKK-related kinase epsilon; inducible I kappa-B kinase; inducible IkappaB kinase; inhibitor of nuclear factor kappa-B kinase subunit epsilon; IKKE; IKKI; IKK-E; IKK-i; KIAA0151; MGC125294; MGC125295; MGC125297; EC 2.7.11.10
• Gene ID: 9641
• mRNA Refseq: NM_014002
• Protein Refseq: NP_054721
• MIM: 605048
• UniProt ID: Q14164
• Chromosome Location: 1q32.1
• Pathway: Cytosolic DNA-sensing pathway; RIG-I-like receptor signaling pathway; Toll-like receptor signaling pathway; Signaling in Immune system
• Function: ATP binding; IkappaB kinase activity; identical protein binding; nucleotide binding; protein heterodimerization activity; transcription activator activity; transferase activity