Catalog # or name ...
Rabbit Polyclonal antibody to Human XRCC3.
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 202 and 346 of XRCC3
Immunogen affinity purified
Preservative: 0.01% Thimerosal (merthiolate)Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
Store at -20oC or lower.Aliquot to avoid repeated freezing and thawing.
Belongs to the recA family. RAD51 subfamily.
Antigen Gene Information
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 [ Homo sapiens ]
XRCC3; X-ray repair complementing defective repair in Chinese hamster cells 3; DNA repair protein XRCC3; RAD51 like; DNA repair protein XRCC3; RAD51 like; X ray repair complementing defective repair in Chinese hamster; X ray repair complementing defective repair in Chinese hamster cells 3; X ray repair cross complementing protein 3; X-ray repair cross-complementing protein 3; XRCC 3; XRCC3; XRCC3_HUMAN; X-ray repair cross-complementing protein 3; CMM6;
Fluoropyrimidine Activity, organism-specific biosystem; Homologous recombination, organism-specific biosystem; Homologous recombination, conserved biosystem;
ATP binding; DNA binding; DNA-dependent ATPase activity; nucleotide binding;
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