Recombinant Human Natriuretic Peptides B, aa 1-108
Cat.No. : | NPPB-2683H |
Product Overview : | Recombinant Human Natriuretic Peptides B (aa 1-108) is expressed inE. coli. |
- Specification
- Gene Information
- Related Products
Cat. No. : | NPPB-2683H |
Description : | BNP (Brain natriuretic peptide) is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. BNP is a 32 amino acid polypeptide and is co-secreted along with a 76 amino acid N-terminal fragment which is biologically inactive. This protein has biological actions including natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion. It is thought to play a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. |
Source : | E. coli. |
Sequence : | GRAPLGSPGSA SDLETSGLQEQRN HLQGKLSELQVEQTSLEPL QESPRPTG VWKSREVATEG IRGHRKMVLYT LRAPRSPKM VQGSGCFG RKMDRISSSS GLGCKVLRRHM. |
Purity : | Over 95% pure by PAGE. |
Buffer : | 50 mM Tris, 100 mM NaCl, pH 7.4. |
MW : | 8390 Da. |
Contents : | 10 μg/100 μg (lyophilized). |
Storage : | 2-8 °C (lyophilized); - 20 °C (dissolved); Repeated thawing and freezing must be avoided. |
Gene Name : | NPPB natriuretic peptide precursor B [ Homo sapiens ] |
Synonyms : | NPPB; Natriuretic peptides B; BNP; OTTHUMP00000002506; OTTHUMP00000044486; Gamma-brain natriuretic peptide; brain type natriuretic peptide; natriuretic peptide precursor B; natriuretic protein; Gamma-brain natriuretic peptide; GC-B |
Gene ID : | 4879 |
mRNA Refseq : | NM_002521 |
Protein Refseq : | NP_002512 |
MIM : | 600295 |
UniProt ID : | P16860 |
Chromosome Location : | 1p36.2 |
Function : | diuretic hormone activity |
Products Types
◆ Recombinant Protein | ||
NPPB-8050H | Synthetic Human Brain Natriuretic Peptide 32 | +Inquiry |
NPPB-6042H | Recombinant Human NPPB Protein, GST-tagged | +Inquiry |
NPPB-1298H | Recombinant Human NPPB Protein, GST-tagged | +Inquiry |
NPPB-388H | Recombinant Human NPPB Protein, His&SUMO-tagged | +Inquiry |
Nppb-390R | Recombinant Rat Nppb Protein, His&SUMO-tagged | +Inquiry |
◆ Native Protein | ||
Nppb-5459R | Native Rat Natriuretic Peptide B | +Inquiry |
NPPB-8052R | Native Rat Brain Natriuretic Peptide-32 | +Inquiry |
◆ Lysates | ||
NPPB-3734HCL | Recombinant Human NPPB 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionElevated NPPB levels are associated with fluid overload, providing valuable information for clinicians in managing patients with conditions like edema.
Yes, monitoring NPPB levels over time can help assess the effectiveness of treatments and interventions in managing cardiovascular conditions.
Normal ranges of NPPB may vary with age and gender. Understanding these variations is essential for accurate clinical interpretation.
While NPPB is a valuable marker, clinicians should consider factors like renal function and comorbidities that may affect its interpretation.
NPPB regulates blood pressure by promoting vasodilation and natriuresis. Understanding its levels can guide the management of hypertension.
Customer Reviews (3)
Write a reviewThey actively engage with researchers, comprehending their specific experimental needs, and offering tailored services accordingly.
This collaborative partnership facilitates a seamless and efficient research process, as the manufacturer aligns their support and services with my unique requirements.
The manufacturer's excellent technical support, commitment to innovation, and customer-centric approach further reinforce its suitability for my research.
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