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Cat.No.
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CPBT-50072CR
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Product Overview
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Chicken Polyclonal antibody to Rat VIM.
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Antigen Description
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class-III intermediate filament of the cytoskeleton; along with desmin (the subunit specifically expressed in muscle), vimentin is specific for mesenchymal tissue
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Isotype
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IgY
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Immunogen
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Recombinant full length protein (Rat)
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Host
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Chicken
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Species
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Rat
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Specificity
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Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitts lymphoma cell lines. Expressed in many hormone-independent mammary carcinoma cell lines.
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Formulation
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Vimentin is found in connective tissue and in the cytoskeleton.
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Purity Detail
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IgY fraction
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Applications
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ICC/IF, IHC-FoFr, IF
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Storage
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Store at +4oC short term (1-2 weeks). Aliquot and store at -20oC long term. Avoid repeated freeze / thaw cycles.
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Sequence similarities
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Belongs to the intermediate filament family.
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Antigen Gene Information
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Gene Name
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Vim vimentin [ Rattus norvegicus ]
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Official Symbol
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VIM
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Synonyms
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VIM; vimentin; FLJ36605; VIM; VIME_HUMAN; vimentin;
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GeneID
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81818
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mRNA Refseq
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NM_031140
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Protein Refseq
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NP_112402
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Pathway
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Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem; Caspase-mediated cleavage of cytoskeletal proteins, organism-specific biosystem;
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Function
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identical protein binding; kinase binding; protein C-terminus binding; protein C-terminus binding; protein binding;
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Download Datasheet:
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