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Native Human FN1 protein

Cat.No. : FN1-2708H
Product Overview : Native Human Fibronectin protein was purified from Human blood/plasma.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined.
Source : Human blood/plasma
Species : Human
Form : Lyophilized from 20 mM Hepes, 150 mM NaCl, pH 7.4
Molecular Mass : 550000
Purity : >95% by SDS-PAGE
Notes : Although the starting material was prior to initiation of the manufacturing process, and was found negative or nonreactive for anti HIV-1/2, HIV-1 RNA, HBsAg, STS, anti-HCV, HCV RNA, anti-Hbcore and anti-HTLV, extreme caution should be used when handling this material as there is a margin of error in all tests, and testing does not always diclose pathogens or other harmful substances contained in blood/plasma products.
Storage : Store it at 4 centigrade
Reconstitution : Reconstitute with 1.36 milliliters of water to achieve 1.5 mg/ml. Following reconstitution, allow product to dissolve for at least 30 minutes at 37 centigrade. A small amount of undissolved material may remain.
Gene Name : FN1 fibronectin 1 [ Homo sapiens ]
Official Symbol : FN1
Synonyms : FN1; fibronectin 1; fibronectin; CIG; cold insoluble globulin; FINC; GFND2; LETS; migration stimulating factor; MSF; cold-insoluble globulin; migration-stimulating factor; FN; FNZ; ED-B; GFND; DKFZp686H0342; DKFZp686I1370; DKFZp686F10164; DKFZp686O13149;
Gene ID : 2335
mRNA Refseq : NM_002026
Protein Refseq : NP_002017
MIM : 135600
UniProt ID : P02751

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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which organs and tissues is the FN1 protein expressed? 12/21/2019

It is expressed in a variety of organs and tissues, including skin, kidneys, cardiovascular system, liver, etc.

How about the FN1 protein in inflammatory diseases? 09/09/2019

FN1 protein is involved in the migration, adhesion and activation of inflammatory cells during the inflammatory response, and plays an important role in the development of inflammation.

Have regulators of the FN1 protein been identified? 07/16/2019

Yes, multiple factors have been found to regulate the expression and function of FN1 protein, including transcription factors, growth factors, etc.

What is the relationship between FN1 protein and tumor metastasis? 06/26/2019

FN1 protein is involved in the invasion and metastasis of tumor cells, which can provide matrix support and guide signals to promote the migration and invasion of tumor cells.

What is the role of FN1 protein in wound healing? 04/15/2019

This protein is involved in key steps such as fibrosis, angiogenesis and interstitial cell proliferation in the wound healing process, and plays an important role in wound repair.

How about the mechanism of action of FN1 protein in tissue repair? 04/13/2019

The protein plays an important role in key steps such as extracellular matrix remodeling, cell adhesion, and directed differentiation of mesenchymal stem cells during tissue repair.

Customer Reviews (3)

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Reviews
06/21/2021

    The preservation conditions are wide and the efficiency is high.

    08/14/2019

      Experimental process is convenient, which greatly improves the efficiency of scientific research.

      03/25/2019

        Biological activity of this protein is amazing, and you can see that its production process is very pure, which has a crucial effect on the quality of the product.

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