Recombinant Human Coagulation Factor III (Thromboplastin, Tissue Factor)

• Cat.No.: F3-463H
• Product Overview: Recombinant human tissue factor produced in a Baculovirus transfer vector expression system. It is visualized at 26 kDa on an SDS gel electrophoresis.

Specification

• Cat. No.: F3-463H
• Description: Tissue factor is a cell-surface protein of endothelial cells and monocytes involved in coagulation and inflammation. It is the primary cellular initiator of coagulation cascade, and functions as receptor and cofactor for coagulation Factor VII and VIIa.
• Source: Baculovirus.
• Purity: Greater than 95% per SDS-PAGE.
• Activity: Upon lipidation, Product will promote clotting in a two-stage prothrombin time test.
• Presentation: Screw capped clear glass vials of 2.5 µg of protein lyophilized from 10 mM TRIS-HCl, 150 mM NaCl, 0.01% CHAPS, pH 8.0, with 200 mM mannitol.
• Reconstitution: Add 100 µL of filtered deionized water.
• Storage And Stability: Store lyophilized vials at +2° - +8°C. Store reconstituted protein in aliquots frozen at -20°C or colder, avoid freeze-thaw cycles.

Gene Information

• Gene Name: F3 coagulation factor III (thromboplastin, tissue factor) [ Homo sapiens ]
• Synonyms: coagulation factor III (thromboplastin, tissue factor); TF; TFA; CD142; FLJ17960; F3; tissue factor; thromboplastin;Coagulation factor III; CD142 antigen; Thromboplastin
• Gene ID: 2152
• mRNA Refseq: NM_001993
• Protein Refseq: NP_001984
• MIM: 134390
• UniProt ID: P13726
• Chromosome Location: 1p22-p21
• Pathway: Complement and coagulation cascades; Hemostasis
• Function: cell surface binding; phospholipid binding; protease binding