Recombinant Human TIMP Metallopeptidase Inhibitor 1
Cat.No. : | TIMP1-2530H |
- Specification
- Gene Information
- Related Products
Cat. No. : | TIMP1-2530H |
Description : | Tissue Inhibitor of Metalloproteinases 1, also known as TIMP1 is a widely expressed, secreted protein that functions primarily to inhibit members of a large family of metalloproteinases (MPs). Because of the ability of TIMP-1 to inhibit MPs, it functions in many of the same pathophysiological processes as these enzymes, e.g. wound healing, ovulation, angiogenesis, and cancer cell metastasis. TIMP-1 can also stimulate proliferation and cellular anabolic processes. TIMP-1 is a novel negative regulator of HGF activity during liver regeneration. Overexpression of TIMP-1 could promote renal interstitial fibrosis through the inflammatory pathway, which might be partly induced by upregulating ICAM-1. |
Source : | CHO. |
Biochem/physiol Actions : | TIMP-1 has greater binding efficiency to MMP-9, MMP-1, and MMP-3 than the other MMPs. |
Physical Form : | Supplied in 0.01 M sodium phosphate buffer pH 7.3, 0.15 M NaCl. |
Concentration : | ~500 μg/mL protein. |
Form : | buffered aqueous solution. |
Mol Wt : | mol wt ~29 kDa. |
Storage Temp : | −20°C. |
Gene Name : | TIMP1 TIMP metallopeptidase inhibitor 1 [ Homo sapiens ] |
Synonyms : | TIMP1; TIMP metallopeptidase inhibitor 1; EPA; EPO; HCI; CLGI; TIMP; FLJ90373; tissue inhibitor of metalloproteinase 1; erythroid potentiating activity; fibroblast collagenase inhibitor; tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor); Tissue inhibitor of metalloproteinases; TIMP-1; Collagenase inhibitor; OTTHUMP00000023214; Erythroid-potentiating activity |
Gene ID : | 7076 |
mRNA Refseq : | NM_003254 |
Protein Refseq : | NP_003245 |
MIM : | 305370 |
UniProt ID : | P01033 |
Chromosome Location : | Xp11.3-p11.23 |
Function : | enzyme inhibitor activity; metalloendopeptidase inhibitor activity; protein binding |
Products Types
◆ Recombinant Protein | ||
Timp1-6436M | Active Recombinant Mouse Timp1 Protein, His-tagged | +Inquiry |
TIMP1-4491H | Recombinant Human TIMP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Timp1-410R | Recombinant Rat Timp1 Protein, His-tagged | +Inquiry |
Timp1-01M | Recombinant Mouse Timp1 Protein, His-tagged | +Inquiry |
TIMP1-1034M | Recombinant Mouse TIMP1 Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
TIMP1-91B | Active Native Bovine Thrombin | +Inquiry |
TIMP1-92H | Native Human TIMP-1 | +Inquiry |
TIMP1-30840TH | Native Human TIMP1 | +Inquiry |
◆ Lysates | ||
TIMP1-2678HCL | Recombinant Human TIMP1 cell lysate | +Inquiry |
TIMP1-1490RCL | Recombinant Rat TIMP1 cell lysate | +Inquiry |
TIMP1-2376MCL | Recombinant Mouse TIMP1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket