Recombinant Human Ubiquitin-like Modifier Activating Enzyme 1

• Cat.No.: UBA1-58H
• Product Overview: Recombinant Human Ubiquitin-like Modifier Activating Enzyme 1 was expressed inSf9 cells.

Specification

• Cat. No.: UBA1-58H
• Description: Ubiquitin Activating Enzyme (E1) is responsible for the first step in ubiquitin-protein isopeptide bond formation. E1 catalyzes the activation of the C-terminal carboxyl group of ubiquitin by forming a high-energy thioester bond in an ATP-dependent manner.
• Source: Sf9 cells.
• Form: Solution in 50 mM HEPES pH 8.0.
• Storage: −70°C.

Gene Information

• Gene Name: UBA1 ubiquitin-like modifier activating enzyme 1 [ Homo sapiens ]
• Synonyms: UBA1; ubiquitin-like modifier activating enzyme 1; A1S9; A1ST; GXP1; UBE1; A1S9T; AMCX1; SMAX2; UBA1A; UBE1X; MGC4781; UBA1, ubiquitin-activating enzyme E1 homolog A; A1S9T and BN75 temperature sensitivity complementing; ubiquitin-activating enzyme E1; EC 6.3.2.19
• Gene ID: 7317
• mRNA Refseq: NM_003334
• Protein Refseq: NP_003325
• MIM: 314370
• UniProt ID: P22314
• Chromosome Location: Xp11.23
• Pathway: Parkinson"s disease; Ubiquitin mediated proteolysis
• Function: ATP binding; ligase activity; nucleotide binding; small protein activating enzyme activity; protein binding