Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human UBA7, His-tagged

Cat.No. : UBA7-629H
Product Overview : Recombinant Human UBA7 isproduced inE. coliand fused at the C-terminus to a His-tag.
  • Specification
  • Gene Information
  • Related Products
Cat. No. : UBA7-629H
Description : The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.
Source : E. coli.
Purity : >95%. Purified by Ni-affinity chromatography.
Application : Activation of ISG15 for ISGylation of specific proteins in presence of dedicated E2 conjugating/E3 ligase enzymes. ISGylation pathway studies. Test proteins for ISG15 E3 ligase activity. Test proteins as potential targets for ISG15 modification.
Storage : -80°C.
Gene Name : UBA7 ubiquitin-like modifier activating enzyme 7 [ Homo sapiens ]
Synonyms : UBA7; ubiquitin-like modifier activating enzyme 7; UBA1, ubiquitin-activating enzyme E1 homolog B; UBA7, ubiquitin-activating enzyme E1; ubiquitin-activating enzyme 7; ubiquitin-activating enzyme E1 homolog; ubiquitin-activating enzyme E1-like; ubiquitin-activating enzyme E1-related protein; ubiquitin-activating enzyme-2; ubiquitin-like modifier-activating enzyme 7; D8; UBE2; UBA1B; UBE1L; MGC12713
Gene ID : 7318
mRNA Refseq : NM_003335
Protein Refseq : NP_003326
MIM : 191325
UniProt ID : P41226
Chromosome Location : 3p21
Pathway : Parkinson"s disease; Ubiquitin mediated proteolysis
Function : ATP binding; ISG15 activating enzyme activity; ligase activity; nucleotide binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All UBA7 Products

Required fields are marked with *

My Review for All UBA7 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends