Catalog # or name ...
Rabbit Polyclonal antibody to Human CPLX2.
Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release. Two transcript variants encoding the same protein have been found for this gene.
A synthetic peptide from an internal region of Human CPLX2 conjugated to an immunogenic carrier protein.
Nervous system. In hippocampus and cerebellum, expressed mainly by excitatory neurons. Down-regulated in brain cortex from patients suffering from Huntington disease, bipolar disorder or major depression. Down-regulated in cerebellum from patients with schizophrenia.
WB, IHC-P, IHC-Fr
Preservative: NoneConstituents: Whole serum, 1X PBS
Store at +4oC short term (1-2 weeks). Aliquot and store at -20oC (add glycerol to a final volume of 40% for extra stability). Avoid repeated freeze / thaw cycles.
Belongs to the complexin/synaphin family.
Antigen Gene Information
CPLX2 complexin 2 [ Homo sapiens ]
CPLX2; complexin 2; complexin-2; CPX 2; DKFZp547D155; 921 L; Complexin 2; Complexin II; Complexin-2; Complexin2; ComplexinII; CPLX 2; Cplx2; CPLX2_HUMAN; CPX 2; CPX II; CPXII; Hfb1; Synaphin 1; Synaphin-1; Synaphin1; CPX II; synaphin 1; synaphin-1; complexin II; CPX2; Hfb1; 921-L; CPX-2;
Synaptic vesicle cycle, organism-specific biosystem; Synaptic vesicle cycle, conserved biosystem;
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