"HPN" Related Products

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GMP Recombinant Human HPN Protein

Cat.No.: HPN-147HG
Product Overview: Recombinant Human HPN, Arg45-Leu417 (Asp161Glu & Arg162Lys), with a C-terminal 10-His tag was produced in NS0 cell under cGMP guidelines.
Source: NS0
Species: Human
Tag : His
Form: Supplied as a 0.2 μm filtered solution in Sodium Acetate and NaCl.
Bio-activity: Measured by its ability to cleave tert-butoxycarbonyl-Gln-Arg-Arg-7-amino-4-methylcoumarin (Boc-QRR-AMC). The specific activity is >20,000 pmol/min/μg.
Molecular Mass: Predicted Molecular Mass: 42 kDa
SDS-PAGE: 40-43 kDa, reducing conditions
N-terminal Sequence Analysis: Arg45-Ser-Asp-Gln-Glu-Pro-Leu-Tyr-Pro-Val
Endotoxin: <1.0 EU per 1 μg of the protein by the LAL method.
Purity: >95%, by SDS-PAGE with silver staining, under reducing conditions.
Storage: Avoid repeated freeze-thaw cycles.
12 months, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Quality Statement: Our GMP proteins are produced according to relevant sections of the following documents: WHO TRS, No. 822, 1992 Annex 1, Good Manufacturing Practices for Biological Products; USP Chapter 1043, Ancillary Materials for Cell, Gene and Tissue-Engineered Products and USP Chapter 92, Growth Factors and Cytokines Used in Cell Therapy Manufacturing.
Gene Name: HPN hepsin [ Homo sapiens ]
Official Symbol: HPN
Synonyms: HPN; hepsin; serine protease hepsin; TMPRSS1; transmembrane protease; serine 1; transmembrane protease serine 1; serine protease hepsin catalytic chain; serine protease hepsin non-catalytic chain;
Gene ID: 3249
mRNA Refseq: NM_002151
Protein Refseq: NP_002142
MIM: 142440
UniProt ID: P05981

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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