Active GMP Recombinant Human MSTN Protein

• Cat.No.: Mstn-121HG
• Product Overview: Recombinant Human MSTN, Asp268-Ser376, was produced in NS0 cell under cGMP guidelines.

Specification

• Source: Mammalian cells
• Species: Human
• Form: Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA.
• Bio-activity: Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. Schwall, R.H. et al. (1991) Method Enzymol. 198:340.
• Molecular Mass: Predicted Molecular Mass: 12.4 kDa
  SDS-PAGE: 12 kDa, reducing conditions; 24 kDa, non-reducing conditions
• N-terminal Sequence Analysis: Asp-Phe-Gly-Leu-Asp-(Cys)-Asp-Glu-His-Ser
• Endotoxin: <0.10 EU per 1 μg of the protein by the LAL method.
• Purity: >90%, by SDS-PAGE with silver staining.
• Storage: Avoid repeated freeze-thaw cycles.
  12 months, -20 to -70 centigrade as supplied.
  1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
  3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Reconstitution: Reconstitute at 100 μg/mL in 4 mM HCl.
• Quality Statement: Our GMP proteins are produced according to relevant sections of the following documents: WHO TRS, No. 822, 1992 Annex 1, Good Manufacturing Practices for Biological Products; USP Chapter 1043, Ancillary Materials for Cell, Gene and Tissue-Engineered Products and USP Chapter 92, Growth Factors and Cytokines Used in Cell Therapy Manufacturing.
• Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

Gene Information

• Gene Name: MSTN myostatin [ Homo sapiens ]
• Official Symbol: Mstn
• Synonyms: MSTN; myostatin; growth/differentiation factor 8; GDF-8; growth differentiation factor 8; GDF8; MSLHP
• Gene ID: 2660
• mRNA Refseq: NM_005259
• Protein Refseq: NP_005250
• MIM: 601788
• UniProt ID: O14793