Active GMP Recombinant Human TGFB1 Protein
Cat.No. : | TGFB1-134HG |
Product Overview : | Recombinant Human TGFB1, Ala279-Ser390, was produced in CHO cell under cGMP guidelines. |
- Specification
- Gene Information
- Related Products
Source : | CHO cell |
Species : | Human |
Form : | Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA. |
Bio-activity : | Measured by its ability to inhibit the IL-4-dependent proliferation of HT‑2 mouse T cells. Tsang, M. et al. (1995) Cytokine 7:389. The specific activity of recombinant human TGF-beta 1 GMP is approximately 2.5 x 10^4 U/μg, which is calibrated against human TGF‑ beta 1 Standard (NIBSC code: 89/514). |
Molecular Mass : | Predicted Molecular Mass: 12.8 (monomer) kDa SDS-PAGE: 12 kDa, reducing conditions; 24 kDa, non-reducing conditions |
N-terminal Sequence Analysis : | Ala-Leu-Asp-Thr-Asn-Tyr-(Cys)-Phe-Ser-Ser |
Endotoxin : | <0.10 EU per 1 μg of the protein by the LAL method. |
Purity : | >97%, by SDS-PAGE with silver staining. |
Storage : | Avoid repeated freeze-thaw cycles. 12 months, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Reconstitution : | Reconstitute at 100 μg/mL in 4 mM HCl. |
Quality Statement : | Our GMP proteins are produced according to relevant sections of the following documents: WHO TRS, No. 822, 1992 Annex 1, Good Manufacturing Practices for Biological Products; USP Chapter 1043, Ancillary Materials for Cell, Gene and Tissue-Engineered Products and USP Chapter 92, Growth Factors and Cytokines Used in Cell Therapy Manufacturing. |
Shipping : | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Gene Name : | TGFB1 transforming growth factor, beta 1 [ Homo sapiens ] |
Official Symbol : | TGFB1 |
Synonyms : | TGFB1; transforming growth factor, beta 1; DPD1, TGFB; transforming growth factor beta-1; Camurati Engelmann disease; CED; TGFbeta; TGF-beta-1; TGF-beta 1 protein; LAP; DPD1; TGFB; |
Gene ID : | 7040 |
mRNA Refseq : | NM_000660 |
Protein Refseq : | NP_000651 |
MIM : | 190180 |
UniProt ID : | P01137 |
Products Types
◆ Recombinant Protein | ||
TGFB1-299H | Recombinant Active Human TGFB1 Protein, His-tagged(C-ter) | +Inquiry |
TGFB1-706H | Recombinant Human TGFB1 Protein, MYC/DDK-tagged | +Inquiry |
TGFB-13H | Recombinant Human TGFB1 Protein, Fc-tagged | +Inquiry |
TGFB1-301P | Recombinant Active Pig TGFB1 Protein, His-tagged(C-ter) | +Inquiry |
TGFB1-72H | Recombinant Human TGFB1 Protein (AA 30-390), N-GFP/His-Tagged | +Inquiry |
◆ Native Protein | ||
TGFB1-21H | Active Native Human TGF- β1 | +Inquiry |
◆ Lysates | ||
TGFB1-2662HCL | Recombinant Human TGFB1 cell lysate | +Inquiry |
TGFB1-001HCL | Recombinant Human TGFB1 cell lysate | +Inquiry |
TGFB1-803RCL | Recombinant Rat TGFB1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionTGFB1 stimulates the activity of cells involved in bone formation (osteoblasts) and plays a role in regulating bone resorption by influencing osteoclast function.
Potential side effects of anti-TGFB1 therapies may include immune system suppression, gastrointestinal issues, and skin reactions.
TGFB1 levels have been studied as potential biomarkers for diseases like cancer and fibrosis, aiding in diagnosis and monitoring disease progression.
TGFB1 plays a critical role in wound healing by stimulating the formation of new blood vessels, promoting the production of extracellular matrix, and aiding in the migration of cells to the wound site.
TGFB1 can induce the production of excessive extracellular matrix proteins, leading to tissue scarring and fibrosis in organs such as the liver, lung, and kidneys.
Customer Reviews (3)
Write a reviewThe impressive performance of the TGFB1 protein both in ELISA assays and protein electron microscopy structure analysis makes it a highly versatile and recommended choice for scientists across various disciplines.
Its reliability and efficacy in generating high-quality data make it an indispensable tool in the quest for unraveling the mysteries of protein structure and function.
The TGFB1 protein's excellent performance in ELISA ensures accurate and reproducible results, enhancing the reliability of experimental data.
Ask a Question for All TGFB1 Products
Required fields are marked with *
My Review for All TGFB1 Products
Required fields are marked with *
Inquiry Basket