Human IDO1 Inhibitor Screening Assay Kit (384)
Cat.No. : | Kit-1758 |
Product Overview : | L-tryptophan (L-Trp) is an essential amino acid necessary for protein synthesis in mammalian cells and the L-Trp to kynurenine (Kyn) pathway is firmly established as a key regulator of innate and adaptive immunity. Catabolism of L-Trp to Kyn maintains an immunosuppressive microenvironment by starving immune cells of L-Trp and releasing degradation products of L-Trp that have immunosuppressive functions. Indoleamine 2,3- dioxygenases (IDO1 & IDO2), two of the rate limiting enzymes in this pathway, are upregulated in many tumors, providing cancer cells with an avenue for immune evasion. |
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Size : | 384 reactions |
Applications : | Useful for the study of IDO1 enzymology, screening inhibitors, and selectivity profiling. |
Storage : | Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival |
Products Types
◆ Recombinant Protein | ||
IDO1-3829H | Recombinant Human IDO1 protein, GST-tagged | +Inquiry |
IDO1-2645R | Recombinant Rat IDO1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ido1-2126M | Recombinant Mouse Indoleamine 2,3-dioxygenase 1, His-tagged | +Inquiry |
IDO1-085H | Recombinant Human IDO1 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
IDO1-1419H | Recombinant Human IDO1 Protein (1-403 aa), His-tagged | +Inquiry |
◆ Lysates | ||
IDO1-5300HCL | Recombinant Human IDO1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Write a reviewThe product was kept in perfect condition and delivered on time so that I got the perfect product in the shortest time possible.
Customer service contacted me in a timely manner and helped me solve a lot of problems that arose in my experiments.
The purchased proteins helped me to get satisfactory experimental results.
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