Active Native Agaricus bisporus lectin Protein
| Cat.No. : | Lectin-1760A |
| Product Overview : | This product is the unconjugated Agaricus bisporus lectin and has sugar specificity against Gal(b-1,3)GalNAc (T disaccharide). |
- Specification
- Gene Information
- Related Products
| Description : | Agaricus bisporus lectin (ABL) isolated from the edible white button mushroom, is composed of two to four very similar isolectins, each a tetramer of approximately 17 kD subunits. This lectin binds the Thomsen-Friedenreich antigen, also called T disaccharide, galactosyl (β-1,3) N-acetylgalactosamine. Unlike peanut agglutinin, which does not bind sialylated T antigen, ABL binds either sialylated or asialylated forms. Also, whereas peanut agglutinin has a proliferative effect on cancer cells, ABL is anti-proliferative, apparently without cytotoxicity. ABL binds all blood groups and O-linked glycans of IgA subclasses. Simple mono- and disaccharides are only marginally inhibitory. |
| Source : | Agaricus bisporus |
| Species : | Agaricus bisporus |
| Form : | 10 mM HEPES, pH 7.5, 150 mM NaCl, 0.08% sodium azide |
| Bio-activity : | Sugar Specificity: Gal(b-1,3)GalNAc (T disaccharide) |
| Applications : | Immunofluorescence, Glycobiology |
| Storage : | Refrigerate in the dark. |
| Concentration : | 2 mg/ml |
| Synonyms : | Lectin; ABL |
| UniProt ID : | Q00022 |
| Synonyms : | Lectin; ABL |
| UniProt ID : | Q00022 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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